869720-52-5

Upstream product

• 79265-30-8 2-(trimethylsilyl)thiazole 
• 301532-91-2 (+)-(2R,3R)-3-methoxy-1-benzyl-4-oxoazetidine-2-carbaldehyde 
• 301532-90-1 (3R,4S)-1-Benzyl-4-((S)-1,2-dihydroxy-ethyl)-3-methoxy-azetidin-2-one 
• 100777-91-1 (2S)-2,3-O-isopropylideneglyceraldehyde N-benzylimine 

Downstream Products

• 869720-60-5 (3R,4R)-1-Benzyl-4-[(S)-(tert-butyl-dimethyl-silanyloxy)-thiazol-2-yl-methyl]-3-methoxy-azetidin-2-one 
• 869720-63-8 (3R,4R)-1-Benzyl-3-methoxy-4-((S)-methoxy-thiazol-2-yl-methyl)-azetidin-2-one 
• 869720-56-9 (3R,4S)-1-Benzyl-4-((S)-hydroxy-thiazol-2-yl-methyl)-3-methoxy-azetidin-2-one 

Relevant academic research and scientific papers

Diastereoselectivity enhancement in the 1,3-cycloaddition of β-lactam aldehydes. Application to the synthesis of enantiopure indolizidinone amino esters

Enantiopure α-alkoxy β-lactam acetaldehydes were prepared via the thiazole-based one-carbon homologation. The 1,3-dipolar cycloaddition reaction involving α-alkoxy β-lactam acetaldehyde-derived azomethine ylides gave with excellent diastereoselectivity hi