869726-08-9

Basic information

• Product Name: ethyl 1-(4-ethoxyphenyl)-5-methyl-1,2,3-triazol-4-carboxylate
• Synonyms: ethyl 1-(4-ethoxyphenyl)-5-methyl-1,2,3-triazol-4-carboxylate
• CAS NO: 869726-08-9
• Molecular Weight: 275.307
• Mol File: 869726-08-9.mol

Chemical Properties

• CAS DataBase Reference: ethyl 1-(4-ethoxyphenyl)-5-methyl-1,2,3-triazol-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-(4-ethoxyphenyl)-5-methyl-1,2,3-triazol-4-carboxylate(869726-08-9)
• EPA Substance Registry System: ethyl 1-(4-ethoxyphenyl)-5-methyl-1,2,3-triazol-4-carboxylate(869726-08-9)

Safety Data

• Hazardous Substances Data: 869726-08-9(Hazardous Substances Data)

Upstream product

• 337980-36-6 1-(4-ethoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid 
• 64-17-5 ethanol 
• 98488-09-6 1-azido-4-ethoxybenzene 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 861243-19-8 1-amino-5-[1-(4-ethoxyphenyl)-5-methyl-1,2,3-triazol-4-yl]-2-sulfanyl-1,3,4-triazole 
• 869726-09-0 1-(4-ethoxyphenyl)-5-methyl-1,2,3-triazol-4-carbonylhydrazine 

Relevant articles and documents

Design, synthesis and biological studies of some new imidazole-1,2,3-triazole hybrid derivatives

Some new 4-((1H-imidazol-1-yl)diarylmethyl)-5-methyl-1-aryl-1H-1,2,3-triazoles 7a-i were designed and synthesized by the one-pot reaction of diaryl-(1-aryl-5-methyl-1H-1,2,3-triazol-4-yl)methanol compounds with 1H-imidazole. The new compounds 7a-i were ch

Primary discovery of 1-aryl-5-substituted-1H-1,2,3-triazole-4-carboxamides as promising antimicrobial agents

Three series of novel 1H-1,2,3-triazole-4-carboxamides: 1-aryl-5-alkyl/aryl-1H-1,2,3-triazole-4-carboxamides, 1-aryl-5-amino-1H-1,2,3-triazole-4-carboxamides and 1,2,3-triazolo[1,5-a]quinazoline-3-carboxamides were synthesized via base-mediated click azide reactions. Compounds were evaluated for their antimicrobial activities against primary pathogens: Gram-positive and Gram-negative bacterial strains Escherichia coli, Klebsiella pneumonia, Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, as well as fungal strain Cryptococcus neoformans var. grubii and Candida albicans. Compounds exhibiting moderate to good activities were selected for SAR analysis. Several 5-methyl-1H-1,2,3-triazole-4-carboxamides 4d, 4l, 4r, showed potent antibacterial effect against S. aureus. On the contrary, 5-amino-1H-1,2,3-triazole-4-carboxamide 8b and [1,2,3]triazolo[1,5-a]quinazoline-3-carboxamide 9a were active against pathogenic yeast C. albicans. Thus, compound 4l under 1 μM demonstrated 50% growth inhibition against S. aureus. At the same concentration, the compound 9a killed approx. 40% of C. albicans cells. In general, these compounds demonstrated selective action and no significant impact on the viability of human keratinocytes of HaCaT line.

Design, synthesis, and anticancer activity evaluation of novel aziridine-1,2,3-triazole hybrid derivatives

Some new 1-aryl-4-[(aziridine-1-yl)diaryl-methyl]-5-methyl-1H-1,2,3-triazole derivatives 7j–s were synthesized by the one-pot reaction of diaryl-(1-aryl-5-methyl-1H-1,2,3-triazol-4-yl)methanol compounds 6j–s formed from 1-aryl-5-methyl-1H-1,2,3-triazole-4

Synthesis of some novel 3,6-bis(1,2,3-triazolyl)-s-triazolo[3,4-b]-1,3,4- thiadiazole derivatives

The cyclization of 1-amino-2-mercapto-5-[1-(4-ethoxyphenyl)-5-methyl-1,2,3- triazol-4-yl]-1,3,4-triazole which was synthesized from p-ethoxyaniline with various triazole acid in absolute phosphorus oxychloride yields 3,6-bis(1,2,3-triazolyl)-s-triazolo[3,

The synthesis and crystal structure of new 3,6-bis[1-(4-ethoxyphenyl)-5- methyl-1,2,3- triazol-4-yl]-s-triazolo[3,4-b]-1,3,4-thiadiazole

The 3,6-bis[1-(4-ethoxyphenyl)-5-methyl-1,2,3-triazol-4-yl]-s-triazolo[3,4- b]-1,3,4-thiad- iazole was synthesized from p-ethoxyaniline to 8 with 1-(4-ethoxyphenyl)-5-methyl-1,2,3-triazol-4-caroxylic acid. The yielded product 9 was investigated with X-ray