869743-37-3Relevant academic research and scientific papers
Method for preparing diaryl propane compound
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Paragraph 0025-0033, (2019/05/02)
The invention relates to the technical field of organic synthesis, in particular to a preparation method of a diaryl propane compound. The preparation method of the diaryl propane compound comprises the following steps: mixing sodium borohydride and Lewis acid in an organic solvent under the protection of inert gas, and slowly adding 1, 3-diaryl acetone, heating and stirring, cooling a reaction solution after the reaction is complete, pouring the reaction solution into water and stirring, extracting, drying, filtering and concentrating the obtained crude product, and recrystallizing to obtainthe product 1, 3-diaryl propane. The preparation process disclosed by the invention has the advantages of low cost, mild and easily controlled reaction conditions, simplicity in aftertreatment, less used organic solvents, environmental friendliness and the like, large-scale industrial production is easily realized.
A 2, 4 - dimethoxy - tolyl -4 - propyl resorcinol synthesis method (by machine translation)
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Paragraph 0030; 0032; 0033; 0035, (2018/10/02)
The invention discloses a 2, 4 - dimethoxy - tolyl - 4 - propyl resorcinol synthesis method, which belongs to the technical field of the synthesis. The method comprises: 2, 4 - dimethoxy - 3 - methyl - acetophenone, 2, 4 - [...] - benzene formaldehyde and strong alkali in aqueous and organic solvent in the mixed systems A, for - 5 °C — 10 °C under the conditions of the reaction, the reaction after the completion of the extraction, to obtain the intermediate I; intermediate I, zinc amalgam and hydrochloric acid under reflux conditions in the reaction, the reaction after the completion of the extraction, to obtain the intermediate II; intermediate II catalytic hydrogenation reaction 2, 4 - dimethoxy - tolyl - 4 - propyl resorcinol. The method obtained product purity is greater than 98%, yield stability, with a generation cycle is short, the operation is convenient and easy industrial production and the like. (by machine translation)
COMPOUNDS AND METHODS FOR PREPARATION OF DIARYLPROPANES
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Page/Page column 18-19, (2012/10/08)
Compounds of structure (I): including stereoisomers, tautomers and salts thereof, wherein R1, R2, R3, R4, R5, R6, X, Y and Z are as defined herein. Such compounds are useful for the preparation of diarylpropane compounds. Methods for the preparation of compounds of structure (I) are also disclosed, as are methods employing compounds of structure (I) for the preparation of diarylpropanes.
