728911-59-9

Basic information

• Product Name: 2,4-diisopropoxyacetophenone
• Synonyms: 2,4-diisopropoxyacetophenone
• CAS NO: 728911-59-9
• Molecular Weight: 236.311
• Mol File: 728911-59-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,4-diisopropoxyacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-diisopropoxyacetophenone(728911-59-9)
• EPA Substance Registry System: 2,4-diisopropoxyacetophenone(728911-59-9)

Safety Data

• Hazardous Substances Data: 728911-59-9(Hazardous Substances Data)

Usage

General Description

2,4-diisopropoxyacetophenone is a chemical compound with the molecular formula C13H18O3. It is a clear, colorless liquid with a faint odor. 2,4-diisopropoxyacetophenone is commonly used as a photoinitiator in the formulation of UV-curable coatings, inks, and adhesives. It acts as a sensitizer when exposed to UV light, initiating the polymerization process in these materials. Additionally, 2,4-diisopropoxyacetophenone is used as a reagent in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. It is important to handle this chemical with care and follow proper safety protocols when working with it, as it may be harmful if ingested or inhaled, and can cause skin and eye irritation.

Upstream product

• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 75-26-3 isopropyl bromide 

Downstream Products

• 1417453-14-5 2’,4’-diisopropoxy-3,4-dimethoxychalcone 
• 1417453-13-4 2’,3,4’-triisopropoxy-4-methoxychalcone 
• 104236-80-8 2′,4′-dihydroxy-3,4-dimethoxychalcone 
• 13323-67-6 2’,3,4’-trihydroxy-4-methoxychalcone 
• 487-52-5 butein 
• 961-29-5 isoliquirtigenin 
• 1400999-45-2 1-(3-(2,4-diisopropdxyphenyl)propyl)-2,4-dimethoxy-3-methylbenzene 
• 869743-37-3 1-(2,4-dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)propane 
• 1400999-30-5 (E)-1-(2,4-diisopropdxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)prop-2-en-1-one 
• 728911-79-3 3'-hydroxy-2'-(3-methyl-2-butenyl)-7,4',6'-triisopropoxyisoflavone 
• 728911-71-5 ethyl 5'-bromo-7,2',4'-triisopropoxyisoflavone-2-carboxylate 
• 728911-78-2 5'-(3-methyl-2-butenyloxy)-7,2',4'-triisopropoxyisoflavone 

Relevant articles and documents

Reactivity assessment of chalcones by a kinetic thiol assay

The electrophilic nature of chalcones (1,3-diphenylprop-2-en-1-ones) and many other α,β-unsaturated carbonyl compounds is crucial for their biological activity, which is often based on thiol-mediated regulation processes. To better predict their biological activity a simple screening assay for the assessment of the second-order rate constants (k2) in thia-Michael additions was developed. Hence, a clear structure-activity relationship of 16 differentially decorated hydroxy-alkoxychalcones upon addition of cysteamine could be established. Moreover, amongst other naturally occurring α,β-unsaturated carbonyl compounds k2 values for curcumin and cinnamaldehyde were gained while cinnamic acids or esters gave no or very slow reactions.

Kwakhurin, a unique isoflavone with rejuvenating activity from "kwao keur": Further characterization by 2D-NMR spectrometry and synthesis of triisopropylkwakhurin

Kwakhurin (5), a characteristic isoflavone component of Pueraria mirifica which has been used in folk medicine as "kwao keur" for rejuvenating purpose, was structurally approached by 2D-NMR experiments. Furthermore, the synthesis of kwakhurin (5) was attempted starting from the methyl ketone (12). Thus, deoxybenzoin derivative (22) was prepared by Friedel-Crafts acylation after protection of the phenolic function with a triisopropyl group. Modification of the substituents, O-prenylation, prenyl 1,3-rearrangement, and O-methylation afforded kwakhurin triisopropyl ether (38).