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Upstream product

• 17626-40-3 4-cyano-1,2-phenylenediamine 
• 50670-55-8 4-(4-cyanophenyl)-benzaldehyde 
• 87199-17-5 4-formylphenylboronic acid, 
• 623-00-7 4-bromobenzenecarbonitrile 

Relevant academic research and scientific papers

Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents

A series of near-linear biphenyl benzimidazole diamidines 5a-h were synthesized from their respective diamidoximes (4a-h), through the bis-O-acetoxyamidoxime, followed by hydrogenation in glacial acetic acid/ethanol in the presence of Pd-C. Compounds 4a-h

DICATIONIC TRIARYL ANALOGS AS ANTI-PROTOZOAN AGENTS

Novel dicationic, heterocyclic triaryl compounds are useful in the treatment of microbial infections, such as Trypanosoma brucei rhodesiense infection and Plasmodium falciparum infection. These compounds are accordingly useful in treating second-stage human African trypanosomiasis. Pharmaceutical formulations comprising these compounds can be used in methods of treating microbial infections.