869788-92-1Relevant academic research and scientific papers
Synthesis of a resveratrol analogue with high ceramide-mediated proapoptotic activity on human breast cancer cells
Minutolo, Filippo,Sala, Giusy,Bagnacani, Annalisa,Bertini, Simone,Carboni, Isabella,Placanica, Giorgio,Prota, Giovanni,Rapposelli, Simona,Sacchi, Nicoletta,Macchia, Marco,Ghidoni, Riccardo
, p. 6783 - 6786 (2005)
Resveratrol, a natural product with a stilbene structure, exerts profound proapoptotic activity in human cancer cells, by triggering the accumulation of ceramide, a bioactive sphingolipid. We studied the biological effects of seven methoxylated and/or nap
Identification of a terphenyl derivative that blocks the cell cycle in the G0-G1 phase and induces differentiation in leukemia cells
Roberti, Marinella,Pizzirani, Daniela,Recanatini, Maurizio,Simoni, Daniele,Grimaudo, Stefania,Di Cristina, Antonietta,Abbadessa, Vincenzo,Gebbia, Nicola,Tolomeo, Manlio
, p. 3012 - 3018 (2007/10/03)
To further explore the SAR of resveratrol-related trans-stilbene derivatives, here we describe the synthesis of (a) a series of 3,5-dimethoxy analogues in which a variety of substituents were introduced at positions 2′, 3′, 4′, and 5′ of the stilbene scaf
