869791-42-4 Usage
Uses
Different sources of media describe the Uses of 869791-42-4 differently. You can refer to the following data:
1. N-Methyl Pemetrexed is an impurity of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes.
2. N-Methyl Pemetrexed (Pemetrexed EP Impurity A) is an impurity of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes.
Check Digit Verification of cas no
The CAS Registry Mumber 869791-42-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,7,9 and 1 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 869791-42:
(8*8)+(7*6)+(6*9)+(5*7)+(4*9)+(3*1)+(2*4)+(1*2)=244
244 % 10 = 4
So 869791-42-4 is a valid CAS Registry Number.
869791-42-4Relevant articles and documents
Synthesis and physicochemical characterization of the impurities of pemetrexed disodium, an anticancer drug
Michalak, Olga,Gruza, Mariusz M.,Witkowska, Anna,Bujak, Iwona,Cmoch, Piotr
, p. 10004 - 10031 (2015/08/06)
A physicochemical characterization of the process-related impurities associated with the synthesis of pemetrexed disodium was performed. The possibility of pemetrexed impurities forming has been mentioned in literature, but no study on their structure has been published yet. This paper describes the development of the synthesis methods for these compounds and discusses their structure elucidation on the basis of two-dimensional NMR experiments and MS data. The identification of these impurities should be useful for the quality control during the production of the pemetrexed disodium salt.
