869794-46-7Relevant academic research and scientific papers
Convenient one-pot synthesis of chiral tetrahydropyridines via a multicomponent reaction
Noel, Romain,Fargeau-Bellassoued, Marie-Claude,Vanucci-Bacque, Corinne,Lhommet, Gerard
body text, p. 1948 - 1954 (2009/04/04)
The multicomponent condensation of various β-dicarbonyl compounds, acrolein and (S)-2-phenylglycinol was found to provide a one-pot access to chiral 6-carbonyl-3-phenyl-2,3,8,8a-tet-rahydro-7H-[l,3]oxazolo[3,2-a]pyridines. The value of this methodology is illustrated by the short and efficient synthesis of (-)-lupinine.
Synthesis of new chiral 6-carbonyl 2,3,8,8a-tetrahydro-7H-oxazolo[3,2-a] pyridines
Noel, Romain,Vanucci-Bacque, Corinne,Fargeau-Bellassoued, Marie-Claude,Lhommet, Gerard
, p. 9044 - 9047 (2007/10/03)
The preparation of new chiral 6-carbonyl 2,3,8,8a-tetrahydro-7H-oxazolo[3, 2-a]pyridines by an efficient two-step procedure is described.
