86983-14-4

Upstream product

• 92-52-4 biphenyl 
• 7439-93-2 lithium 
• 86983-13-3 methyl 2-(1-phenyl-2,5-cyclohexadien-1-yl)acetate 

Downstream Products

• 912581-39-6 (1-phenyl-cyclohexa-2,5-dienyl)-acetaldehyde 
• 519-73-3 triphenylmethane 
• 75287-00-2 N,N-dimethyl-2-(1-phenyl-2,5-cyclohexadien-1-yl)ethylamine 
• 86983-15-5 2-(1-phenyl-2,5-cyclohexadien-1-yl)ethyl methanesulfonate 

Relevant academic research and scientific papers

Metal-Free Transfer Hydroiodination of C-C Multiple Bonds

The design and a gram-scale synthesis of a bench-stable cyclohexa-1,4-diene-based surrogate of gaseous hydrogen iodide are described. By initiation with a moderately strong Br?nsted acid, hydrogen iodide is transferred from the surrogate onto C-C multiple bonds such as alkynes and allenes without the involvement of free hydrogen iodide. The surrogate fragments into toluene and ethylene, easy-to-remove volatile waste. This hydroiodination reaction avoids precarious handling of hydrogen iodide or hydroiodic acid. By this, a broad range of previously unknown or difficult-to-prepare vinyl iodides can be accessed in stereocontrolled fashion.

Metal-Free Transfer Hydrobromination of C-C Triple Bonds

A transfer hydrobromination of C-C triple bonds inititated by Br?nsted acids is reported. Hydrogen bromide is released stepwise from a bench-stable cyclohexa-1,4-diene-based surrogate, generating biphenyl and ethylene as waste. A range of vinyl bromides was prepared from terminal and internal, mainly acceptor-substituted alkynes with good functional-group tolerance.

Phenyl-cyclohexadiene-alkylamine derivatives

Cyclohexadiene derivatives of the formula STR1 wherein R1,R2,R3 and R4 are as hereinafter set forth, are described. The compounds of formula I are useful as analgesic agents.