86984-23-8Relevant academic research and scientific papers
A New and Convenient Synthesis of Alkyl and Aryl Pyrimidines
Martinez, A. Garcia,Herrera, A.,Martinez, R.,Teso, E.,Garcia, A.,et al.
, p. 1237 - 1241 (2007/10/02)
Vinyl triflates 1, which are obtained easily from the corresponding ketones, react in an excess of pure nitrile (80 deg C/20 hours) to form tri- and tetra-substituted alkyl and arylpyrimidines 4 and 5 in good yields (45-87percent).An isomeric mixture of p
PREPARATION OF ALKYL- AND PHENYL-SUBSTITUTED PYRIMIDINES
Martinez, A. Garcia,Fernandez, A. Herrera,Alvarez, R. Martinez,Vilar, E. Teso,Fraile, A. Garcia,et. al.
, p. 1929 - 1932 (2007/10/02)
Vinyltrifluoromethanesulfonates (triflates) 1, which are obtained from the corresponding ketones, react in an excess of pure nitriles (acetonitrile, propionitrile, benzonitrile) at 80 deg C (20 h) to form substituted pyrimidines 5 and 8 in good yields
Nickel-catalyzed Addition or Coupling Reactions of Grignard Reagents with Halopyrimidines
Elmoghayar, Mohamed R. H.,Groth, Per,Undheim, Kjell
, p. 109 - 114 (2007/10/02)
Phenylmagnesium bromide with NiCl2(dppp) catalysis adds selectively to the unsubstituted position in 2,4-dichlro-5-chloro(fluoro)pyrimidine.X-Ray structure analysis of the hydrolyzed adduct shows an infinite chain by N1 - N3' hydrogen bonding.The hydrolyz
