Cas 869891-50-9,5-(5-chloro-thiophen-2-yl)-1-(2',4'-dichloro-phenyl)-4-methyl-1H-pyrazol-3-carboxylic acid ethyl ester

869891-50-9

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Basic information

Product Name: 5-(5-chloro-thiophen-2-yl)-1-(2',4'-dichloro-phenyl)-4-methyl-1H-pyrazol-3-carboxylic acid ethyl ester
Synonyms: 5-(5-chloro-thiophen-2-yl)-1-(2',4'-dichloro-phenyl)-4-methyl-1H-pyrazol-3-carboxylic acid ethyl ester
CAS NO:869891-50-9
Molecular Formula:
Molecular Weight: 415.727
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 5-(5-chloro-thiophen-2-yl)-1-(2',4'-dichloro-phenyl)-4-methyl-1H-pyrazol-3-carboxylic acid ethyl ester(CAS DataBase Reference)
NIST Chemistry Reference: 5-(5-chloro-thiophen-2-yl)-1-(2',4'-dichloro-phenyl)-4-methyl-1H-pyrazol-3-carboxylic acid ethyl ester(869891-50-9)
EPA Substance Registry System: 5-(5-chloro-thiophen-2-yl)-1-(2',4'-dichloro-phenyl)-4-methyl-1H-pyrazol-3-carboxylic acid ethyl ester(869891-50-9)

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Hazard Codes: N/A
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Safety Statements: N/A
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RTECS:
HazardClass: N/A
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Hazardous Substances Data: 869891-50-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 869891-50-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,8,9 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 869891-50:
(8*8)+(7*6)+(6*9)+(5*8)+(4*9)+(3*1)+(2*5)+(1*0)=249
249 % 10 = 9
So 869891-50-9 is a valid CAS Registry Number.

869891-50-9Upstream product

869891-50-9Downstream Products

869891-50-9Relevant academic research and scientific papers

Hair growth stimulator property of thienyl substituted pyrazole carboxamide derivatives as a cb1 receptor antagonist with in vivo antiobesity effect

Srivastava, Brijesh Kumar,Soni, Rina,Patel, Jayendra Z.,Joharapurkar, Amit,Sadhwani, Nisha,Kshirsagar, Samadhan,Mishra, Bhupendra,Takale, Vijay,Gupta, Sunil,Pandya, Purvi,Kapadnis, Prashant,Solanki, Manish,Patel, Harilal,Mitra, Prasenjit,Jain, Mukul R.,Patel, Pankaj R.

scheme or table, p. 2546 - 2550 (2010/01/16)

A few thienyl substituted pyrazole derivatives were synthesized to aid in the characterization of the cannabinoid receptor antagonist and also to serve as potentially useful antiobesity agent. Structural requirements for selective CB1 receptor antagonistic activity of 5-thienyl pyrazole derivatives included the structural similarity with potent, specific antagonist rimonabant 1. Compound 3 has been identified as a hair growth stimulator and an antiobesity agent in animal models.

Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H- pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor anta

Tseng, Shi-Liang,Hung, Ming-Shiu,Chang, Chun-Ping,Song, Jen-Shin,Tai, Chia-Liang,Chiu, Hua-Hao,Hsieh, Wan-Ping,Lin, Yinchiu,Chung, Wan-Ling,Kuo, Chun-Wei,Wu, Chien-Huang,Chu, Cheng-Ming,Tung, Yen-Shih,Chao, Yu-Sheng,Shia, Kak-Shan

experimental part, p. 5397 - 5412 (2009/07/01)

Replacing the conventional pyrazole 5-aryl substituent of 1 (SR141716A) with the 2-thienyl moiety appended with an appropriate alkynyl unit, a novel class of 5-(5-alkynyl-2-thienyl)pyrazole derivatives, behaving as highly potent CB1 receptor antagonists w

PYRAZOLE COMPOUNDS

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Page/Page column 6; 8, (2008/06/13)

This invention relates to pyrazole compounds of formula (I) shown below: Each variable in formula (I) is defined in the specification. These compounds can be used to treat cannabinoid-receptor mediated disorders.

THIOPHENE COMPOUNDS

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Page/Page column 14, (2008/06/13)

This invention relates to thiophene compounds of formula (I) shown below: Each variable in formula (I) is defined in the specification. These compounds can be used to treat cannabinoid-receptor mediated disorders.

PYRAZOLE DERIVATIVES HAVING AFFINITY FOR CB1 AND/OR CB2 RECEPTORS

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Page/Page column 14-15, (2010/02/14)

Pyrazole derivatives of the following formula (I), having affinity for the cannabinoidergic CB1 and/or CB2 receptors: ???wherein:R is a group selected from:C1-C10 alkyl;aryl, arylalkyl or arylalkenyl, not substituted or having from o

Pharmaceutical compounds

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Page/Page column 10-11, (2010/02/14)

Pyrazole derivatives of the following formula (I), having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein: R is a group selected from: C1-C10 alkyl; aryl, arylalkyl or arylalkenyl, not substituted or having from o

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