86998-00-7Relevant academic research and scientific papers
Chiral modular n-butyllithium aggregates: nBuLi complexes with anisyl fencholates
Goldfuss, Bernd,Steigelmann, Melanie,Rominger, Frank,Urtel, Heiko
, p. 4456 - 4464 (2007/10/03)
Chiral, enantiopure aggregates are formed spontaneously by mixing solutions of n-butyllithium with anisyl fenchols. X-ray crystal analyses reveal the structures of these aggregates with different ortho substituents in the anisyl moieties (X), X=H (1-H), S
Meta Functionalization of Anilines and Phenol
Fukui, Mineo,Ikeda, Toshiya,Oishi, Takeshi
, p. 466 - 475 (2007/10/02)
Base-promoted proton abstraction from ?-(N-tert-butyldimethylsilyl-N-methylaniline)chromium tricarbonyl (3) took place predominantly at the meta position and variously meta-substituted N-methylacetanilides 4 were obtained after reactions with electrophiles followed by oxidative decomplexation and N-acetylation.Application of the present method to variously N,N-disubstituted anilines 5 and phenols 7 was then examined and the corresponding meta substituted anilines 6 and phenol 9 were obtained.Keywords - metalation of aromatic ring; chromium tricarbonyl complex; tert-butyl dimethylsilyl protecting group; meta-substituted anilines; meta-substituted phenol; electrophilic substitution
