870-62-2

Basic information

• Product Name: HEXAMETHONIUM IODIDE
• Synonyms: 6-hexanediaminium,n,n,n,n’,n’,n’-hexamethyl-diiodide;esametonioioduro;hexamethoniumdiiodide;hexamethylenebis(trimethyl-ammoniudiiodide;hexathide;HEXAMETHYLENE-BIS-TRIMETHYLAMMONIUM IODIDE;HEXAMETHONIUM IODIDE
• CAS NO: 870-62-2
• Molecular Formula: C₁₂H₃₀N₂*2I
• Molecular Weight: 456.19
• EINECS: 212-797-4
• Mol File: 870-62-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: HEXAMETHONIUM IODIDE(CAS DataBase Reference)
• NIST Chemistry Reference: HEXAMETHONIUM IODIDE(870-62-2)
• EPA Substance Registry System: HEXAMETHONIUM IODIDE(870-62-2)

Safety Data

• Hazardous Substances Data: 870-62-2(Hazardous Substances Data)

Usage

General Description

Hexamethonium iodide is a quaternary ammonium compound that acts as a ganglionic blocker, exerting its effect primarily on the autonomic nervous system. It is commonly used as a hypertensive agent to lower blood pressure by blocking the transmission of nerve impulses in ganglia. Hexamethonium iodide is also used in research to study the effects of autonomic nerve transmission and has been investigated as a potential treatment for conditions such as high blood pressure, but its clinical use is limited due to adverse effects and the development of more effective antihypertensive medications.

InChI:InChI=1/C12H30N2.2HI/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2

Upstream product

• 111-18-2 N,N,N',N'-tetramethylhexamethylenediamine 
• 74-88-4 methyl iodide 
• 6055-52-3 hexane-1,6-diamine dihydrochloride 
• 2163-00-0 1,6-dichlorohexane 
• 75-50-3 trimethylamine 

Relevant articles and documents

Systematic structure control of ammonium iodide salts as feasible UCST-type forward osmosis draw solutes for the treatment of wastewater

A variety of UCST-type thermoresponsive ammonium iodide salts is systematically designed and synthesised with desired aqueous solubility, phase-transition temperature, osmolality change, phase-transition concentration range, stability, and toxicity by controlling the ionic interactions, hydrophobicity, and symmetry of the salt structure. Suitable draw solutes can be selected based on the characteristics of the ammonium iodide salts as well as the feed solutions for feasible forward osmosis (FO)-based water purification. In this research, highly concentrated wastewater from a flue gas desulfuriser (FGD), with osmotic pressure three times higher than seawater, is targeted for purification by FO using the draw solutes. Two ammonium iodide salts (HM8I and HM10I) show a remarkable water flux from the wastewater samples and significantly lower salt leakage compared to conventional draw solutes. The osmolality of the phase-separated draw solution drops to less than one tenth of that of the initial feed solution, and reverse osmosis or nanofiltration can be applied to the solution with much lower external pressure for the final purification to produce fresh water. This systematic approach to the design and selection of suitable draw solutes can be an effective strategy for future practical FO-based wastewater treatment and seawater desalination.

A convenient synthesis of [11C]paraquat and other [N-methyl-11C]bisquaternary ammonium compounds

[11C]Paraquat was synthesized by the reaction of [11C]methyl triflate with the mono-triflate salt of 1-methyl-[4,4′]bipyridinyl. The product was selectively separated from the precursor by a microcolumn of Chelex 100 ion exchange resin. The method was applied to the synthesis of a variety of [N-methyl-11C]bisquaternary ammonium compounds. This is the first reported use of a chelating cation exchange resin for the selective purification of organic dications. Copyright