870010-43-8Relevant academic research and scientific papers
Gold-Catalyzed Fluorination–Hydration: Synthesis of α-Fluorobenzofuranones from 2-Alkynylphenol Derivatives
Wang, Qiang,Jiang, Yu,Sun, Run,Tang, Xiang-Ying,Shi, Min
, p. 14739 - 14745 (2016/10/03)
The AuI-catalyzed fluorination–hydration of 2-alkynylphenol derivatives in the presence of Selectfluor [1-chloromethyl-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate)] has been developed. This method provides straightforward a
On the trapping of vinylgold intermediates
Hashmi, A. Stephen K.,Ramamurthi, Tanuja Dondeti,Rominger, Frank
experimental part, p. 971 - 975 (2010/06/13)
An internal aryl-substituted ortho-alkynylphenol and a similar aniline with stoichiometric amounts of N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene- gold tosylate [(IPr)AuOTs] and triethylamine gave the aurated heterocycles as stable intermediates of
3,3-bis(arylbenzofurans) via a gold-catalyzed domino process
Auzias, Mathieu G.,Neuburger, Markus,Wegner, Hermann A.
supporting information; experimental part, p. 2443 - 2448 (2010/11/18)
A new heterogeneous gold-catalyzed system for the domino cyclization oxidative coupling of 2-alkynyl phenols for the formation of 3,3-bisbenzofurans was developed. The substrate and the catalyst scope as well as the reaction conditions were investigated and optimized. This method provides access to this novel structural theme in two steps starting from commercially available chemicals. The molecular structure of the 3,3-bisbenzofurans was confirmed by single-crystal X-ray analysis. Georg Thieme Verlag Stuttgart · New York.
Synthesis of novel oxygen heterocycles: 1,10-dioxa-cyclopenta[a]fluorene and benzo[b]naphtho[2, 1-d]furans via D?tz intramolecular benzannulation
Sen, Subhabrata,Kulkarni, Parag,Borate, Kailaskumar,Pai, Nandini R.
scheme or table, p. 4128 - 4131 (2009/12/01)
Novel fused heterocycles 1,10-dioxa-cyclopenta[a]fluorene and benzo[b]naphtho[2, 1-d]furans were synthesized via D?tz intramolecular benzannulation of alkyne tethered aryloxy chromium Fischer carbenes.
Intramolecular alkyne hydroalkoxylation and hydroamination catalyzed by iridium hydrides
Li, Xingwei,Chianese, Anthony R.,Vogel, Tiffany,Crabtree, Robert H.
, p. 5437 - 5440 (2007/10/03)
(Chemical Equation Presented) Iridium(III) hydrides prove to be air-stable active catalysts for intramolecular hydroalkoxylation and hydroamination of internal alkynes with proximate nucleophiles. The cyclization follows highly selective 6-endo-dig regiochemistry when regioselectivity is an issue.
Heterocycles by PtCl2-catalyzed intramolecular carboalkoxylation or carboamination of alkynes
Fuerstner, Alois,Davies, Paul W.
, p. 15024 - 15025 (2007/10/03)
PtCl2 constitutes a convenient catalyst for intramolecular hydroalkoxylation, carboalkoxylation, hydroamination, and carboamination reactions of alkynes, effecting the formation of substituted benzo[b]furan, indole-, and isochromene-1-one derivatives, respectively. This procedure allows for the transfer of (substituted) allyl, methoxymethyl (MOM), benzyloxymethyl (BOM), and (trimethylsilyl)ethoxymethyl (SEM) groups from oxygen to carbon and is compatible with functional groups that are susceptible to oxidative insertion of low valent metal species previously used for similar purposes. Although some of the reactions can even be carried out in air, the rates are significantly increased when conducted under an atmosphere of CO. A mechanistic rationale is proposed, implying activation of the alkyne by the carbophilic Pt(2+) template as the primary step of the catalytic cycle. Copyright
