870061-94-2

Upstream product

• 870061-93-1 furo[2,3-b]pyridin-3(2H)-one O-methyl-oxime 
• 27038-48-8 furo<2,3-b>pyridin-3(2H)-one 

Downstream Products

• 1421618-78-1 2-(2,4-dichloro-phenyl)-N-(2,3-dihydro-furo[2,3-b]pyridin-3-yl)-acetamide 
• 1421618-79-2 2-(2,4-dichloro-phenyl)-N-(2,3-dihydro-furo[2,3-b]pyridin-3-yl)-acetamide 

Relevant academic research and scientific papers

HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS

The invention relates to heterocyclic amide derivatives of formula (I), wherein R1, R2, R3, R4, R5, X, Y and n are as defined in the description, their preparation and their use as pharmaceutically active compounds.

HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS

The invention relates to heterocyclic amide derivatives of formula (I), wherein R1, R2, R3, R4, R5, X, Y and n are as defined in the description, their preparation and their use as pharmaceutically active compounds.

AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE

A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R 5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.