870075-18-6

Upstream product

• 870075-17-5 (2S,3R,4R,5S,6S)-3-(tert-Butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4,6-trimethyl-decan-1-ol 
• 852049-56-0 tert-Butyl-((Z)-(2S,3R,4S)-6-iodo-3-methoxymethoxy-2,4-dimethyl-hept-5-enyloxy)-dimethyl-silane 
• 870074-98-9 tert-Butyl-[(1S,2R,3S,4S)-1-((R)-2-iodo-1-methyl-ethyl)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-octyloxy]-dimethyl-silane 
• 398518-64-4 (2S,3R,4R,5S,6S,Z)-3-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6-trimethyldeca-7,9-dien-1-ol 

Downstream Products

• 1334327-46-6 C₅₀H₉₁NO₉Si₂ 
• 1334327-45-5 C₅₀H₉₁NO₉Si₂ 
• 1334327-35-3 (3S,4Z,6S,7S,8S,9Z,12S,13R,14S,15S,16S)-15-(carbamoyloxy)-3,7,13-trihydroxy-6,8,10,12,14,16-hexamethylicosa-4,9-dienyl 3-(dimethylamino)benzoate 
• 1334327-40-0 (8Z,10S,11S,12S,13Z,16S,17R)-17-((2R,3S,4S)-3-(4-methoxybenzyloxy)-4-methyloctan-2-yl)-11-(methoxymethyloxy)-2,2,3,3,10,12,14,16,19,19,20,20-dodecamethyl-4,18-dioxa-3,19-disilahenicosa-8,13-dien-7-one 
• 1334327-36-4 (2R,3R,4S,5Z,8S,9R,10R,11S,12S,Z)-9-(tert-butyldimethylsilyloxy)-11-(4-methoxybenzyloxy)-3-(methoxymethyloxy)-2,4,6,8,10,12-hexamethylhexadec-5-enal 
• 870075-21-1 (5R,6S)-6-[(3Z,8Z)-(2S,5S,6S,7S,11S,12R,13R,14S,15S)-2,12-Bis-(tert-butyl-dimethyl-silanyloxy)-14-(4-methoxy-benzyloxy)-6-methoxymethoxy-5,7,9,11,13,15-hexamethyl-nonadeca-3,8-dienyl]-5-methyl-tetrahydro-pyran-2-one 
• 870075-19-7 (Z)-(2S,3R,4S,8S,9R,10R,11S,12S)-9-(tert-Butyl-dimethyl-silanyloxy)-11-(4-methoxy-benzyloxy)-3-methoxymethoxy-2,4,6,8,10,12-hexamethyl-hexadec-5-en-1-ol 

Relevant academic research and scientific papers

Design, synthesis and biological evaluation of a simplified fluorescently labeled discodermolide as a molecular probe to study the binding of discodermolide to tubulin

The design, synthesis, and biological evaluation of a simplified fluorescently labeled discodermolide analogue possessing a dimethylaminobenzoyl fluorophore has been achieved. Stereoselective Suzuki coupling and Horner-Wadsworth-Emmons reaction comprised

Design, synthesis, and biological evaluation of simplified analogues of (+)-discodermolide. Additional insights on the importance of the diene, the C(7) hydroxyl, and the lactone

(Chemical Equation Presented) The design, synthesis, and biological evaluation of seven totally synthetic analogues of the antitumor agent (+)-discodermolide are reported. Saturation of the terminal diene system, alteration of the substituents on the lact