870083-18-4

Upstream product

• 5680-79-5 glycine ethyl ester hydrochloride 
• 89-98-5 2-chloro-benzaldehyde 
• 616-34-2 methoxycarbonylmethylamine 

Downstream Products

• 939799-28-7 methyl (1S,3R,3aS,6aR)-4,6-dioxo-3-(o-chlorophenyl)-5-phenyl-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate 
• 1169983-20-3 methyl (1R,3S,3aR,6aS)-4,6-dioxo-3-(o-chlorophenyl)-5-phenyl-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate 
• 1309870-98-1 (2R,4R,5R)-4-tert-butyl 2-methyl 5-(2-chlorophenyl)-4-(hydroxymethyl)-pyrrolidine-2,4-dicarboxylate 

Relevant academic research and scientific papers

Axially chiral BINIM and Ni(II)-catalyzed highly enantioselective 1,3-dipolar cycloaddition reactions of azomethine ylides and N-arylmaleimides

(Chemical Equation Presented) Axially chiral BINIM-Ni(II) complexes are effective catalysts in the asymmetric 1,3-dipolar cycloaddition reactions of azomethine ylides and N-arylmaleimides to give the corresponding adducts in good yields and up to 95% enan

Chiral thiophosphoramide and selenophosphoramide ligands in the Cu(I)-promoted catalytic enantioselective 1,3-dipolar cycloaddition reactions of azomethine ylides and pyrrole-2,5-dione derivatives

Chiral C2-symmetric diphenylthiophosphoramide ligand L1 prepared from C2-symmetric (1S,2S)-(-)-1,2-diphenylethylenediamine was found to be a fairly effective chiral ligand for Cu(I)-promoted 1,3-dipolar cycloaddition of imines and py

Cu(I)-catalyzed highly exo-selective and enantioselective [3 + 2] cycloaddition of azomethine ylides with acrylates

(Chemical Equation Presented) A novel Cu(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides with acrylates has been developed. Up to 98/2 exo/endo selectivity and up to 98% enantiomeric excess have been achieved.

Bifunctional AgOAc-catalyzed asymmetric [3 + 2] cycloaddition of azomethine ylides

(Chemical Equation Presented) A bifunctional AgOAc-catalyzed asymmetric cycloaddition of azomethine ylides with electronic-deficient alkenes was developed using ferrocenyloxazoline-derived N,P ligands. The reactive metal-bound azomethine ylide dipole is formed by the deprotonation with acetate, and extra base is not necessary. The reactions proceed with high enantioselectivity. This method provides an efficient and convenient route to optically active pyrrolidine derivatives.