870141-47-2Relevant academic research and scientific papers
Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity
Ermann, Monika,Riether, Doris,Walker, Edward R.,Mushi, Innocent F.,Jenkins, James E.,Noya-Marino, Beatriz,Brewer, Mark L.,Taylor, Malcolm G.,Amouzegh, Patricia,East, Stephen P.,Dymock, Brian W.,Gemkow, Mark J.,Kahrs, Andreas F.,Ebneth, Andreas,Loebbe, Sabine,O'Shea, Kathy,Shih, Daw-Tsun,Thomson, David
, p. 1725 - 1729 (2008)
A high-throughput screening campaign resulted in the discovery of a highly potent dual cannabinoid receptor 1 (CB1) and 2 (CB2) agonist. Following a thorough SAR exploration, a series of selective CB2 full agonists were identified.
