870150-57-5Relevant academic research and scientific papers
Synthesis and relative bioavailability of meptazinol benzoyl esters as prodrugs
Lu, Meiyan,Zhang, Chengji,Hao, Jinglai,Qiu, Zhuibai
, p. 2607 - 2609 (2005)
Three meptazinol benzoyl esters (1-3) were synthesized as prodrugs to minimize the first-pass effect of meptazinol and improve the bioavailability. Among these three esters, compound 3 showed better bioavailability than the parent meptazinol. Further, the
