870283-61-7

Upstream product

• 74199-04-5 4,5,6-trimethoxy-3',4'-mehylendioxybiphenyl-2-carbaldehyde 
• 263764-23-4 (S)-3-propanoyl-4-benzyl-1,3-thiazolidine-2-thione 

Downstream Products

• 870283-65-1 (1S,2R)-1-(2-Benzo[1,3]dioxol-5-yl-3,4,5-trimethoxy-phenyl)-2-methyl-but-3-en-1-ol 
• 870283-67-3 (4R,5S)-5-(2-Benzo[1,3]dioxol-5-yl-3,4,5-trimethoxy-phenyl)-4-methyl-dihydro-furan-2-one 
• 870283-66-2 (1S,2R)-1-(2-Benzo[1,3]dioxol-5-yl-3,4,5-trimethoxy-phenyl)-2-methyl-butane-1,4-diol 
• 870283-69-5 (2S,3S)-3-(2-Benzo[1,3]dioxol-5-yl-3,4,5-trimethoxy-phenyl)-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-propionaldehyde 
• 870283-64-0 [(1S,2R)-1-(2-Benzo[1,3]dioxol-5-yl-3,4,5-trimethoxy-phenyl)-2-methyl-but-3-enyloxy]-tert-butyl-dimethyl-silane 
• 870283-63-9 (2R,3S)-3-(2-Benzo[1,3]dioxol-5-yl-3,4,5-trimethoxy-phenyl)-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-propan-1-ol 

Relevant academic research and scientific papers

Synthesis of eupomatilone-6 and assignment of its absolute configuration

The Zn-mediated Barbier reaction of the biarylaldehyde 8 with crotyl bromide followed by hydroboration and oxidation provided the γ-butyrolactones 4 and 5. The stereoselective installation of methyl group at C-3 by using LiHMDS and MeI completed the synth