870527-61-0

Basic information

• Product Name: (E)-(2R,4S,5R)-(-)-(3-bromo-2-methyl-allyl)-(4-isopropyl-2-phenyl-[1,3]dioxan-5-yl)-amine
• Synonyms: (E)-(2R,4S,5R)-(-)-(3-bromo-2-methyl-allyl)-(4-isopropyl-2-phenyl-[1,3]dioxan-5-yl)-amine
• CAS NO: 870527-61-0
• Molecular Weight: 354.287
• Mol File: 870527-61-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-(2R,4S,5R)-(-)-(3-bromo-2-methyl-allyl)-(4-isopropyl-2-phenyl-[1,3]dioxan-5-yl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(2R,4S,5R)-(-)-(3-bromo-2-methyl-allyl)-(4-isopropyl-2-phenyl-[1,3]dioxan-5-yl)-amine(870527-61-0)
• EPA Substance Registry System: (E)-(2R,4S,5R)-(-)-(3-bromo-2-methyl-allyl)-(4-isopropyl-2-phenyl-[1,3]dioxan-5-yl)-amine(870527-61-0)

Safety Data

• Hazardous Substances Data: 870527-61-0(Hazardous Substances Data)

Upstream product

• 1015841-29-8 [(E)-3-bromo-2-methylprop-2-en-(E)-ylidene]-((2R,4S,5R)-4-isopropyl-2-phenyl-[1,3]-dioxan-5-yl)amine 
• 870527-58-5 (2R,4S,5R)-(-)-5-amino-4-isopropyl-2-phenyl[1,3]dioxane 
• 69143-05-1 (E)-4-methyl-pent-2-en-1-ol 
• 870527-57-4 (2R,3S)-(-)-2-azido-4-methyl-1-pentane-1,3-diol 
• 89459-98-3 (2S,3S)-2,3-epoxy-4-methyl-1-pentanol 
• 15790-86-0 ethyl-4-methyl-2-(E)-penteneoate 
• 870527-70-1 (2R,4S,5R)-(-)-5-azido-4-isopropyl-2-phenyl[1,3]dioxane 

Downstream Products

• 186833-31-8 7-epi-omuralide 
• 154226-60-5 omuralide 
• 145451-97-4 (3R,4S,5R,1'S)-4-hydroxy-5-(1'-hydroxy-2'-methylpropyl)-3-methylpyrrolidin-2-one-5-carboxylic acid 
• 876950-16-2 (3R,4R,5S,6S,8R)-6-isopropyl-3-methyl-8-phenyl-7,9,11,13-tetraoxa-12-thiocarbonyl-1-azaspiro[4.5]decan-2-one 
• 876952-15-7 (2S,3S,4R)-2-((S)-1-benzoyloxy-2-methyl-propyl)-3-hydroxy-4-methyl-5-oxo-pyrrolidine-2-carboxylic acid 
• 876950-23-1 (2S,3S,4S)-2-((S)-1-benzoyloxy-2-methyl-propyl)-3-hydroxy-4-methyl-5-oxo-pyrrolidine-2-carboxylic acid 
• 876950-18-4 (3R,4R,5S,6S,8R)-3,4-dihydroxy-6-isopropyl-3-methyl-8-phenyl-7,9-dioxa-1-azaspiro[4.5]decan-2-one 
• 876952-13-5 (S)-1-((2S,3S,4R)-3-hydroxy-2-hydroxymethyl-4-methyl-5-oxo-pyrrolidin-2-yl)-2-methyl-propyl benzoate 
• 876950-22-0 benzoic acid (S)-1-((2S,3S,4S)-3-hydroxymethyl-4-methyl-5-oxo-pyrrolidin-2-yl)-2-methylpropyl ester 
• 876950-25-3 benzoic acid 1-(2-formyl-3-hydroxy-4-methyl-5-oxo-pyrrolidin-2-yl)-2-methyl-propyl ester 
• 876950-24-2 (S)-1-((2S,3S,4S)-2-formyl-3-hydroxy-4-methyl-5-oxo-pyrrolidin-2-yl)-2-methyl-propyl benzoate 
• 876950-20-8 (3R,4S,5S,6S,8R)-4-hydroxy-6-isopropyl-3-methyl-8-phenyl-7,9-dioxa-1-azaspiro[4.5]decan-2-one 
• 876950-21-9 (3S,4S,5S,6S,8R)-4-hydroxy-6-isopropyl-3-methyl-8-phenyl-7,9-dioxa-1-azaspiro[4.5]decan-2-one 
• 876950-17-3 1-chloro-6-isopropyl-3-methyl-8-phenyl-7,9-dioxa-1-aza-spiro[4.5]dec-3-en-2-one 

Relevant articles and documents

Enantioselective total syntheses of omuralide, 7-epi-omuralide, and (+)-lactacystin

(Chemical Equation Presented) An alkylidene carbene 1,5-CH insertion has been used as a key step in an enantioselective total syntheses of omuralide, its C7-epimer, and (+)-lactacystin. An additional noteworthy feature of the synthesis is the use of a nov

A formal synthesis of (+)-lactacystin

A synthetic route to the neurotrophic agent (+)-lactacystin has been developed utilizing a base-promoted intramolecular alkylidenecarbene C-H insertion as the key transformation. The Royal Society of Chemistry 2005.