870764-93-5Relevant academic research and scientific papers
Structure of aldose condensation products with 2-hydroxyand 2-sulfanylbenzohydrazides
Alekseev,Ershov,Chernitsa,Doroshenko,Lagoda,Yakimovich,Zerova,Pakal'Nis,Shamanin
experimental part, p. 860 - 865 (2010/10/21)
The structure of the condensation products of 2-hydroxy- and 2-sulfanylbenzohydrazides with a series of aldoses (L-arabinose, D-ribose, L-ramnose, D-galactose, D-glucose, D-mannose) was studied by 1H and 13C NMR spectroscopy. The condensation products of monosaccharides with 2-hydroxybenzohydrazide in DMSO-d 6 solution exist as equilibrium mixtures of linear hydrazone and cyclic pyranose and furanose forms, the cyclic tautomers being represented by two stereoisomers (α- and β-anomers). The aldose condensation products with 2-sulfanylbenzohydrazide in the crystalline state have cyclic 1,3,4-benzothiadiazepine structure, while in DMSO-d 6 solution they undergo complete or partial isomerization into cyclic pyranose tautomer.
