87077-84-7

Upstream product

• 917-64-6 methyl magnesium iodide 
• 89201-84-3 4-(4-bromophenyl)-2-butanone 
• 589-15-1 1-bromomethyl-4-bromobenzene 

Downstream Products

• 85964-37-0 1-bromo-4-(3-methyl-2-buten-1-yl)benzene 
• 138624-01-8 1-Bromo-4-(3-methyl-but-3-enyl)-benzene 
• 958640-43-2 4-(4-bromophenyl)-2-methyl-2-trimethylsiloxybutane 
• 1000072-24-1 4-(4-bromophenyl)-2-chloro-2-methylbutane 

Relevant academic research and scientific papers

InCl3-catalyzed cross-coupling of alkyl trimethylsilyl ethers and allylsilanes via an in situ derived combined lewis acid of InCl3 and Me3SiI

(Chemical Equation Presented) Direct Csp3-Csp3 coupling of various aliphatic trimethylsilyl ethers and allylsilanes is effectively catalyzed by InCl3 and I2. The transformation is thought to involve an in situ-derived combined Lewis acid of InCl3 and Me3SiI. The reaction can be used for the construction of quaternary-quaternary and quaternary-tertiary carbon-carbon bonds. This system enabled a highly chemoselective coupling to be conducted with a trimethylsilyl ether including an aryl halide moiety. Furthermore, couplings were possible using an alkynyltri-methylsilane and a trimethylsilyl ketene acetal.

Coupling reaction of alkyl chlorides with silyl enolates catalyzed by indium trihalide

Indium(III) halide catalyzed not only the coupling of alkyl chlorides with silyl enolates derived from esters, ketones, and aldehydes to give a variety of α-alkylated carbonyl compounds but also one-pot, three-component reactions of aldehyde enolate, alkyl chloride, and allylsilane or alkynylsilane.