89201-84-3

Basic information

• Product Name: 4-(4-BROMOPHENYL)-2-BUTANONE
• Synonyms: 4-(4-BROMOPHENYL)-2-BUTANONE;2-Butanone, 4-(4-bromophenyl)-
• CAS NO: 89201-84-3
• Molecular Formula: C₁₀H₁₁BrO
• Molecular Weight: 227.1
• Mol File: 89201-84-3.mol
• Article Data: 31

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-BROMOPHENYL)-2-BUTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-BROMOPHENYL)-2-BUTANONE(89201-84-3)
• EPA Substance Registry System: 4-(4-BROMOPHENYL)-2-BUTANONE(89201-84-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 89201-84-3(Hazardous Substances Data)

Usage

General Description

4-(4-Bromophenyl)-2-butanone is a chemical compound with the molecular formula C10H11BrO. It is a ketone derivative that features a bromine-substituted phenyl group attached to the second carbon of a butanone chain. 4-(4-BROMOPHENYL)-2-BUTANONE is commonly used in organic synthesis and pharmaceutical research as a building block for the preparation of various biologically active molecules. It is also utilized in the production of fragrances, flavors, and as a solvent in chemical processes. The presence of the bromine atom in the phenyl ring makes this compound useful in the creation of diverse chemical structures and functionalities for a wide range of applications.

Upstream product

• 598-32-3 2-hydroxy-3-butene 
• 589-87-7 1,4-bromoiodobenzene 
• 2028-85-5 (4-bromophenyl)diazonium chloride 
• 78-94-4 methyl vinyl ketone 
• 20511-04-0 (E)-4-(4-bromophenyl)but-3-ene-2-one 
• 73183-34-3 bis(pinacol)diborane 
• 5467-74-3 4-Bromophenylboronic acid 
• 1122-91-4 4-bromo-benzaldehyde 
• 1439-36-7 1-triphenylphosphoranylidene-2-propanone 
• 34176-08-4 sodium 4-bromobenzenesulfinate 
• 106-40-1 4-bromo-aniline 
• 1643-30-7 3-(4-bromophenyl)propionic acid 
• 259099-03-1 3-(4-bromophenyl)-N-methoxy-N-methylpropanamide 
• 676-58-4 methylmagnesium chloride 

Downstream Products

• 89201-87-6 2-Trimethylsilanyl-4-(4-trimethylsilanyl-phenyl)-butan-2-ol 
• 939825-19-1 1-bromo-4-(4-bromophenyl)-2-butanone 
• 87077-84-7 4-(4-bromophenyl)-2-methyl-2-butanol 
• 39516-08-0 4-(4-bromophenyl)-2-butanol 
• 20511-04-0 (E)-4-(4-bromophenyl)but-3-ene-2-one 
• 778647-06-6 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butan-2-one 
• 1048954-30-8 4-(4-(3-oxobutyl)phenyl)propanal 
• 1092851-70-1 1-[4-(4-bromophenyl)butyl]-1H-imidazole hydrochloride 
• 1093058-52-6 1-[4-(4-bromophenyl)butyl]-1H-imidazole 
• 939825-12-4 1-((2-(2-(4-bromophenyl)ethyl)-1,3-dioxolan-2-yl)methyl)-1H-imidazole hydrochloride 

Relevant articles and documents

Iron powder and tin/tin chloride as new reducing agents of Meerwein arylation reaction with unexpected recycling to anilines

Simple and rapid route for Meerwein arylation reaction using iron powder or a mixture of tin/tin chloride has been developed. In the presence of iron powder, different aryl diazonium salts reacted with methyl vinyl ketone, acrylates, and isopropenyl acetate. Production of oximes was detected as the main product with acrylates or in a mixture with β-aryl methyl ketones in the case of methyl vinyl ketone. The in situ produced HNO2 from an excess of NaNO2/HCl was trapped by alkyl aryl radical to form oximes in the E configuration form. The presence of tin/tin chloride mixture in the reaction of the aryl diazonium salts with methyl vinyl ketone produced Michael products along with β-aryl methyl ketones. The predicted α-aryl methyl ketones from the reaction of isopropenyl acetate with the diazotized anilines were obtained using iron or tin/tin chloride mixture.

Enantioselective Iridium-Catalyzed Allylation of Acetylenic Ketones via 2-Propanol-Mediated Reductive Coupling of Allyl Acetate: C14-C23 of Pladienolide D

Highly enantioselective catalytic reductive coupling of allyl acetate with acetylenic ketones occurs in a chemoselective manner in the presence of aliphatic or aromatic ketones. This method was used to construct C14-C23 of pladienolide D in half the steps previously required.

BENZYL-, (PYRIDIN-3-YL)METHYL- OR (PYRIDIN-4-YL)METHYL-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS

The present invention relates to compounds of general formula (I), wherein the groups R1 and R2 are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity.