871013-26-2

Usage

Uses

Used in Pharmaceutical Industry:
7-METHYLTHIENO[3,2-D]PYRIMIDINE is used as a building block in the synthesis of pharmaceutical compounds for its ability to contribute to the development of new drugs with potential therapeutic applications. Its unique structure allows for the creation of molecules with specific biological activities, making it a valuable component in medicinal chemistry.
Used in Agrochemical Industry:
In agrochemicals, 7-METHYLTHIENO[3,2-D]PYRIMIDINE serves as a key component in the design and synthesis of novel agrochemicals, potentially enhancing crop protection and yield through its incorporation into pesticides, herbicides, or other agricultural chemicals.
Used in Materials Science:
7-METHYLTHIENO[3,2-D]PYRIMIDINE is utilized as a precursor in materials science for the preparation of advanced materials with specific properties. Its structural attributes can lead to the development of materials with applications in various industries, such as electronics, where it may contribute to the creation of new semiconductors or other functional materials.
Used in Organic Synthesis:
7-METHYLTHIENO[3,2-D]PYRIMIDINE is employed as a versatile precursor in organic synthesis, allowing chemists to construct a wide range of organic compounds with diverse applications. Its reactivity and structural features make it a useful intermediate in the synthesis of complex organic molecules.

Upstream product

• 175137-21-0 4-chloro-7-methylthieno[3,2-d]pyrimidine 
• 175137-13-0 7-methyl-3,4-dihydrothieno[3,2-d]pyrimidin-4-one 
• 85006-31-1 3-amino-4-methyl-2-thiophenecarboxylic acid methyl ester 

Downstream Products

• 1446113-41-2 7-hydroxymethylthieno[3,2-d]pyrimidine 
• 871013-27-3 C₇H₅BrN₂S 

Relevant academic research and scientific papers

ISOINDOLINONE DERIVATIVES AS IRAK4 MODULATORS

Compounds of Formula (0), and stereoisomers and pharmaceutically acceptable salts thereof, as well as methods of use as Interleukin-1 Receptor Associated Kinase (IRAK4) inhibitors are described herein.

Discovery of a potent and highly selective transforming growth factor β receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD)

A novel thienopyrimidinone analog was discovered as a potent and highly selective TAK1 inhibitor using the SBDD approach. TAK1 plays a key role in inflammatory and immune signaling, so TAK1 is considered to be an attractive molecular target for the treatm

THIENO[3,2-D]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES

Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases.

THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASES

Provided are a thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt thereof having inhibitory activity for protein kinase, and a pharmaceutical composition comprising same for prevention and treatment of abnormal cell growth diseases

PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS

Compounds of the formula I or II: wherein X, m, Ar, R1 and R2 are as defined herein. The subject compounds are useful for treatment of IRAK-mediated conditions.