871013-92-2

Basic information

• Product Name: tert-butyl 4-hydroxyisoindoline-2-carboxylate
• Synonyms: tert-butyl 4-hydroxyisoindoline-2-carboxylate;tert-butyl 4-hydroxy-2,3-dihydro-1H-isoindole-2-carboxylate
• CAS NO: 871013-92-2
• Molecular Formula: C₁₃H₁₇NO₃
• Molecular Weight: 235.27898
• Mol File: 871013-92-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 359.5±42.0 °C(Predicted)
• Appearance: /
• Density: 1.205±0.06 g/cm3(Predicted)
• PKA: 9.77±0.20(Predicted)
• CAS DataBase Reference: tert-butyl 4-hydroxyisoindoline-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-hydroxyisoindoline-2-carboxylate(871013-92-2)
• EPA Substance Registry System: tert-butyl 4-hydroxyisoindoline-2-carboxylate(871013-92-2)

Safety Data

• Hazardous Substances Data: 871013-92-2(Hazardous Substances Data)

Usage

General Description

Tert-butyl 4-hydroxyisoindoline-2-carboxylate is a chemical compound with the molecular formula C14H17NO4. It is a ester derivative of 4-hydroxyisoindoline-2-carboxylic acid, and consists of a tert-butyl group attached to the nitrogen atom and a carboxylic acid group. tert-butyl 4-hydroxyisoindoline-2-carboxylate is used in organic synthesis as a building block for the preparation of various pharmaceuticals and agricultural chemicals. It has also shown potential antioxidant and antitumor activities, making it a subject of interest for further research in the field of medicinal chemistry. Additionally, its unique structure and reactivity make it a valuable intermediate in the production of specialty chemicals.

Upstream product

• 1035235-28-9 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoindoline-2-carboxylic acid tert-butyl ester 
• 1035235-27-8 tert-butyl 4-bromo-2,3-dihydro-1H-isoindole-2-carboxylate 
• 491875-13-9 4-hydroxy-2-(4-methoxybenzyl)-1H-isoindole-1,3(2H)-dione 
• 37418-88-5 3-hydroxyphthalic anhydride 
• 135414-50-5 1,3-dioxo-3,3a,7,7a-tetrahydro-4,7-epoxy-2-benzofuran-4(1H)-yl 2,2-dimethyl-propanoate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 127168-73-4 4-methoxy-1H-isoindole 

Relevant articles and documents

INHIBITORS OF MLH1 AND/OR PMS2 FOR CANCER TREATMENT

The present invention relates to compounds of Formula (I) that target the MLH1 and/or PMS2 proteins that are components of the DNA Mismatch Repair (MMR) process: Formula (I) wherein R1, R2, R3, R4, R6

RHO KINASE INHIBITORS

The invention provides novel inhibitors of ROCK1 and/or ROCK2. Also provided are methods of treating diseases and disorders involving inhibiting ROCK1 and/or ROCK2. The present invention includes pharmaceutical compositions comprising the compounds of the invention and a pharmaceutically acceptable carrier and/or diluents. The present invention includes compositions comprising a substantially pure compound of the invention and a pharmaceutically acceptable salt, steroisomer, or hydrate thereof: and a pharmaceutically acceptable excipient and/or diluents.