871086-18-9Relevant academic research and scientific papers
Microwave-induced clay-catalyzed ring opening of N-tosylaziridines: A green approach to achiral and chiral diamines
Nadir, Upender K.,Singh, Anamika
, p. 2083 - 2086 (2005)
N-Tosylaziridines react efficiently with amines in the presence of Montmorillonite K-10 as catalyst under microwave irradiation in solvent-free conditions to yield the corresponding achiral and chiral diamines regio- and stereoselectively, in a few minutes and in high yields.
Synthesis of chiral vicinal C2 symmetric and unsymmetric bis(sulfonamide) ligands based on trans-1,2-cyclohexanediamine by aminolysis of N-tosylaziridines
Bisai, Alakesh,Prasad, B.A. Bhanu,Singh, Vinod K.
, p. 7935 - 7939 (2007/10/03)
The ring opening of N-tosylaziridines with aliphatic amines can be efficiently catalyzed by lithium perchlorate to provide derivatives of the trans-1,2-diamine in high yields. The reaction was used in desymmetrization of several cyclic N-tosylaziridines using chiral amines. Using this strategy, an efficient synthesis of chiral vicinal C2 symmetric bis(sulfonamide) and unsymmetrical bis(sulfonamide) ligands based on trans-1,2-cyclohexanediamine was developed.
