87117-29-1Relevant academic research and scientific papers
Development of a process for triazine-promoted amidation of carboxylic acids
Rayle, Heather L.,Fellmeth, Lisa
, p. 172 - 176 (1999)
A process has been developed for the triazine-promoted amidation of carboxylic acids. We have identified 2,4,6-trichloro-1,3,5-triazine (cyanuric chloride) as a cost-effective reagent for this transformation. The procedure is a suitable alternative to traditional amidation processes when an acid chloride cannot be prepared from the corresponding carboxylic acid due to safety, stability, or handling concerns.
