871210-22-9 Usage
Uses
Used in Pharmaceutical Industry:
(4S,5R)-(-)-4-i-propyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-2-oxazolidinone, 99% is used as a chiral fluorous support for enhancing stereoselectivity in the synthesis of pharmaceutical compounds. Its ability to induce high stereoselectivity in various reactions helps in the production of enantiomerically pure drugs, which is crucial for ensuring the desired therapeutic effects and minimizing potential side effects.
Used in Chemical Research:
In the field of chemical research, (4S,5R)-(-)-4-i-propyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-2-oxazolidinone, 99% serves as a valuable tool for studying reaction mechanisms and developing new synthetic methodologies. Its enantioselective properties make it an attractive candidate for exploring asymmetric catalysis and the development of novel chiral catalysts.
Used in Environmentally Friendly Synthesis:
(4S,5R)-(-)-4-i-propyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-2-oxazolidinone, 99% is used as a green chemistry reagent for reducing the environmental impact of chemical synthesis. The fluorous chain allows for efficient product isolation using minimal amounts of common solvents, thereby reducing waste and the need for hazardous solvents.
Used in High-Throughput Screening:
In the context of high-throughput screening, (4S,5R)-(-)-4-i-propyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)-2-oxazolidinone, 99% is employed as a chiral fluorous support for rapidly evaluating the stereoselectivity of various reactions. This enables chemists to identify the most promising synthetic routes and optimize reaction conditions more efficiently.
Check Digit Verification of cas no
The CAS Registry Mumber 871210-22-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,2,1 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 871210-22:
(8*8)+(7*7)+(6*1)+(5*2)+(4*1)+(3*0)+(2*2)+(1*2)=139
139 % 10 = 9
So 871210-22-9 is a valid CAS Registry Number.
871210-22-9Relevant academic research and scientific papers
Practical synthesis of fluorous oxazolidinone chiral auxiliaries from α-amino acids
Hein, Jason E.,Geary, Laina M.,Jaworski, Ashley A.,Hultin, Philip G.
, p. 9940 - 9946 (2007/10/03)
A series of new fluorous-supported oxazolidinone chiral auxiliaries has been prepared using a versatile and general five-step pathway, starting from readily available chiral α-amino acids. The key feature of this synthesis is the efficient generation of a suitably active perfluoroalkyllithium species. By use of this protocol, the auxiliaries can be obtained in high enantiomeric purity and on multigram scales from L-phenylalanine and L-valine with overall yields as high as 55%. The new methodology also incorporates fluorous solid-phase extraction on the large scale, allowing bulk quantities (up to 25 g) of fluorous compounds to be purified from the crude reaction mixture.
