87127-10-4

Basic information

• Product Name: CARBAMIC ACID, [5-(BENZOYLAMINO)-1H-BENZIMIDAZOL-2-YL]-, METHYL ESTER
• Synonyms: CARBAMIC ACID, [5-(BENZOYLAMINO)-1H-BENZIMIDAZOL-2-YL]-, METHYL ESTER
• CAS NO: 87127-10-4
• Molecular Formula: C₁₆H₁₄N₄O₃
• Molecular Weight: 0
• Mol File: 87127-10-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.454g/cm³
• Refractive Index: 1.753
• CAS DataBase Reference: CARBAMIC ACID, [5-(BENZOYLAMINO)-1H-BENZIMIDAZOL-2-YL]-, METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: CARBAMIC ACID, [5-(BENZOYLAMINO)-1H-BENZIMIDAZOL-2-YL]-, METHYL ESTER(87127-10-4)
• EPA Substance Registry System: CARBAMIC ACID, [5-(BENZOYLAMINO)-1H-BENZIMIDAZOL-2-YL]-, METHYL ESTER(87127-10-4)

Safety Data

• Hazardous Substances Data: 87127-10-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H14N4O3/c1-23-16(22)20-15-18-12-8-7-11(9-13(12)19-15)17-14(21)10-5-3-2-4-6-10/h2-9H,1H3,(H,17,21)(H2,18,19,20,22)

Upstream product

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Relevant articles and documents

Quinone Imine Route to Benzimidazol-2-ylcarbamates. Part 1. Synthesis of Open-chain and Cyclic 5-Acylamino Derivatives.

The synthesis of the N',N''-bismethoxycarbonyl-N-(4-acylaminophenyl)guanidines (4) and (7) is described.Oxidation of these with LTA has led to the benzimidazol-2-ylcarbamates. (8), (9) and (10) through a regiospecific cyclisation of quinone imine intermediates.If the acylamino group is part of a ring, the yield of benzimidazoles (15) increases with the size of the lactam ring.The direction of ring closure may be controlled by electronic and steric factors.

A NOVEL SYNTHESIS OF 5-ACYLAMINOBENZIMIDAZOLE-2-CARBAMATES: INTRAMOLECULAR REGIOSELECTIVE ADDITION TO QUINONE-IMIDES

Oxidation of N',N''-biscarbomethoxy-N-(4-acylamino)phenylguanidines with lead tetraacetate has given novel 5-acylamino-benzimidazole-2-carbamates by a process involving regioselective cyclization of intermediate quinoneimides.