871332-75-1 Usage
General Description
4-CHLORO-3-(PYRROLIDINE-1-CARBONYL)PHENYLBORONIC ACID is a chemical compound with the molecular formula C13H15BClNO3. It is a boronic acid derivative that contains a chloro substituent and a pyrrolidine-1-carbonyl group. 4-CHLORO-3-(PYRROLIDINE-1-CARBONYL)PHENYLBORONIC ACID is commonly used as a reagent in organic synthesis, particularly in Suzuki coupling reactions to form carbon-carbon bonds. It is also used in pharmaceutical research for the development of new drugs and in the production of advanced materials. 4-CHLORO-3-(PYRROLIDINE-1-CARBONYL)PHENYLBORONIC ACID is an important tool in the field of organic chemistry, with a wide range of applications in both academic and industrial settings.
Check Digit Verification of cas no
The CAS Registry Mumber 871332-75-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,3,3 and 2 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 871332-75:
(8*8)+(7*7)+(6*1)+(5*3)+(4*3)+(3*2)+(2*7)+(1*5)=171
171 % 10 = 1
So 871332-75-1 is a valid CAS Registry Number.
871332-75-1Relevant articles and documents
A robust three-step telescoped synthesis of electron-deficient amide substituted arylboronic acids
Zhu, Jason,Razler, Thomas M.,Xu, Zhongmin,Conlon, David A.,Sortore, Eric W.,Fritz, Alan W.,Demerzhan, Roman,Sweeney, Jason T.
scheme or table, p. 438 - 442 (2012/02/03)
A robust three-step telescoped process for the preparation of electron-deficient amide-substituted arylboronic acids from readily available bromobenzoic acids has been developed. An EDC-HOBT-promoted amide formation of a bromobenzoic acid was followed by subjection of the product stream to a palladium-mediated cross-coupling with B2(pin)2. The resultant mixture of the arylboronate ester and arylboronic acid was directly treated with NaIO4, followed by a heptane-MeTHF crystallization, to cleanly afford the corresponding arylboronic acid in good yield. This general procedure was used to synthesize electron-deficient amide-substituted arylboronic acids with a diverse array of electron-withdrawing substituents.
