87143-30-4Relevant articles and documents
Synthesis of Spiro-dihydroquinoline and Octahydrophenanthrene Derivatives via Palladium-Catalyzed Intramolecular Oxidative Arylation
Zang, Zhong-Lin,Karnakanti, Shuklachary,Zhao, Sheng,Hu, Ping,Wang, Zhen,Shao, Pan-Lin,He, Yun
supporting information, p. 1354 - 1357 (2017/03/23)
A method for intramolecular sp2 C-H oxidative arylation of unactivated cyclic olefins has been developed to access spiro-dihydroquinoline and octahydrophenanthrene derivatives in a straightforward and efficient manner. Bearing picolinamide as a directing group, the alkenyl anilines cyclized to afford spiro-dihydroquinolines in moderate to excellent yields via direct oxidative arylation, while the alkenyl benzylamines furnished the octahydrophenanthrene derivatives in moderate yields via sequential oxidative arylation and double acetoxylation.
Efficient hydrolysis of nitriles to amides with hydroperoxide anion in aqueous surfactant solutions as reaction medium
Brinchi, Lucia,Chiavini, Lisa,Goracci, Laura,Di Profio, Pietro,Germani, Raimondo
experimental part, p. 175 - 179 (2010/04/23)
Aliphatic and aromatic nitriles are converted to corresponding amides in a single step via hydrolysis with basic H2O2 in aqueous solution of the surfactant Cetyltrimethylammonium methanesulfonate (CTAOMs). The method has several advantages: use and recycle of water as reaction medium, use of environmentally benign oxidant H2O2, easy product isolation, short reaction time, high yields and selectivity, mild conditions.
2,2,2-Trichloroethylsulphonyl, 2,2,2-Trichloroethoxysulphonyl, and Trifluoroacetyl Isocyanates in β-Lactam Synthesis
Barrett, Anthony G. M.,Fenwick, Ashley,Betts, Michael J.
, p. 299 - 301 (2007/10/02)
Condensation of the title isocyanates with olefins and subsequent dissolving-metal reduction (sulphonyl derivates) or chromatography on Florisil (trifluoroacetyl derivatives) gave several N-unsubstituted β-lactams including two 8-aza-2-oxabicyclooc
