87151-60-8

Usage

Uses

Used in Fragrance Industry:
1-Oxa-spiro[4.5]decan-8-one is used as a key component in the creation of fragrances for its distinctive aromatic properties, contributing to the development of unique scents in perfumes and other scented products.
Used in Flavorings Industry:
In the flavorings industry, 1-Oxa-spiro[4.5]decan-8-one serves as an important ingredient for enhancing the taste profiles of various food and beverage products, leveraging its ability to impart specific flavor characteristics.
Used in Pharmaceutical Industry:
1-Oxa-spiro[4.5]decan-8-one is utilized as a building block in the synthesis of pharmaceutical compounds, where its unique chemical properties are harnessed to develop new drugs with potential therapeutic applications.
Used in Fine Chemicals Production:
1-Oxa-spiro[4.5]decan-8-one plays a crucial role in the production of fine chemicals, where its distinctive chemical properties are employed in various synthesis reactions to create high-quality specialty chemicals for diverse applications.
Used in Organic Synthesis:
1-Oxa-spiro[4.5]decan-8-one is an important intermediate in organic synthesis, contributing to the development of new compounds with potential uses across multiple industries, including pharmaceuticals, agrochemicals, and materials science.

Upstream product

• 142283-61-2 4-(3-butenyl)-4-hydroxy-cyclohexanone ethylene ketal 
• 65682-31-7 1-dioxalane-cyclohexyl-4-spiroTHF 
• 429691-42-9 8-allyl-1,4-dioxaspiro[4.5]decan-8-ol 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 63947-34-2 ketal tetradecane 
• 90214-47-4 4-(3-hydroxypropyl)-4-hydroxy-cyclohexanone ethylene ketal 

Relevant academic research and scientific papers

Oxaspirocyclic Spiro-Substituted Tetramic Acid and Tetronic Acid Derivatives

The present invention relates to novel oxaspirocyclic spirophenyl-substituted tetramic acid and tetronic acid derivatives of the formula (I) in which W, X, Y, Z, A, B, D, Q1, Q2, and G have the meanings given above, to a plurality of

1- (1-CYCLOHEXYL-4-PIPERIDINYL) -1, 3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE DERIVATIVES WHICH HAVE ACTIVITY ON THE M1 RECEPTOR AND THEIR USE IN MEDICINE

Compounds of Formula (I) or a salt thereof are provided: wherein R1, R2, R4, R5, R6, Q and Z are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicamen

Certain aryl substituted pyrrolopyrazines; a new class of gaba brain receptor ligands

This invention encompasses compounds of formula (I) and pharmaceutically acceptable non-toxic salts thereof wherein (Ia) represents (i) or (ii) where n is 0, 1, or 2: R 1 and R 2 are hydrogen or straight or branched chain alkyl groups; Y various organic a

CERTAIN ARYL SUBSTITUTED PYRROLOPYRAZINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS

This invention encompasses compounds of the formula: STR1 and pharmaceutically acceptable non-toxic salts thereof wherein: STR2 represents: STR3 where n is 0, 1, or 2; R 1 and R 2 are hydrogen or straight or branched chain alkyl groups;Y represents

Certain cycloalkyl and azacycloalkyl pyrrolopyridines; a new class of gaba rain receptor ligands

The present invention encompasses compounds of the formula: STR1 and pharmaceutically acceptable non-toxic salts thereof wherein: A represents nitrogen or C--H, andB represents nitrogen or C--H, with the proviso that when A is nitrogen, B is C--H, and whe

CERTAIN ARYL SUBSTITUTED PYRROLOPYRAZINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS

This invention encompasses compounds of the formula: STR1 and pharmaceutically acceptable non-toxic salts thereof wherein: STR2 represents: STR3 where n is 0, 1, or 2; R 1 and R 2 are hydrogen or straight or branched chain alkyl groups;Y represents

CERTAIN CYCLOALKYL AND AZACYCLOALKYL PYRROLOPYRIMIDINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS

The invention encompasses a compound of the formula STR1 and the pharmaceutically acceptable non-toxic salts thereof wherein X, W, Y, R, and R2 are variables.These compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs thereof and are useful in the diagnosis and treatment of anxiety, sleep, and seizure disorders, overdose with benzodiazepine type drugs, and enhancement of alertness.

Analgesic 1-oxa-, aza- and thia-spirocyclic compounds

Mono-Oxa-, thiaspirocyclic-benzene-acetamide and -benzamide compounds of the formula STR1 wherein p, n, m, A, E, R, R1, R2, X, Y and Z are as defined in the specification, e.g., (±)-(5α,7α,9β)-3,4-dichloro-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]benzeneacetamide, and the pharmacologically acceptable salts thereof, are useful as analgesic compounds having low physical dependence liability, compared to morphine and methodone, and low dysphoria side effects. Some of these compounds have potent analgesic activity when administered orally, and some have low CNS sedative side effects. Pharmaceutical compositions and methods for using these compounds as analgesics are disclosed. Processes for preparing this class of compounds are also disclosed.