87152-45-2

Upstream product

• 137789-09-4 (2-[N-(1-methylbenzylamino)]ethyl)(diphenyl)phosphine oxide 
• 2096-78-8 vinyldiphenylphosphine oxide 
• 23901-74-8 Benzyl-diphenyl-vinyl-phosphonium-bromid 
• 7650-91-1 benzyldiphenylphosphane 
• 6104-47-8 ethynyldiphenylphosphine 
• 1079-66-9 chloro-diphenylphosphine 

Relevant academic research and scientific papers

Mixed donor aminophosphine oxide ligands in ruthenium-catalysed asymmetric transfer hydrogenation reactions

A number of mixed-donor aminophosphine ligands have been prepared and their activity and selectivity in asymmetric transfer hydrogenation reactions assessed. Enantioselectivities up to 93% and 80% were achieved for the reduction of acetophenone and propiophenone, respectively.

Using Catalysts to Make Catalysts: Titanium-Catalyzed Hydroamination to Access P,N-Ligands for Assembling Catalysts in One Pot

Using a diamido-bis(amidate) titanium precatalyst, the hydroamination of alkynylphosphines afforded phosphinoenamine products. After reduction, 2-aminophosphines are prepared in excellent yield and on gram scale. A broad variety of alkynylphosphines and primary amines with different electronic and steric features are tolerated in this sequential transformation, enabling the rapid assembly of a collection of ligands. Additionally, intermediate phosphinoenamines can be used directly as proligands for coordination to transition metals using protonolysis or salt metathesis reactions. These transformations result in easy-to-use one pot protocols to prepare metal P,N-complexes for catalysis or small molecule activation.

Enantioselektive Katalysen LX. Addition von optisch aktiven Aminen an P-substituierte Olefine

The addition of the optically active amines (-)-1-phenylethylamine, (+)-1-phenylethylamine, and (+)-3-aminomethylpinane to diphenylvinylphosphine oxide or 1,1-bis(diphenylphosphino)ethene sulfide gives new PN compounds which were used as cocatalysts in the cross coupling of 1-phenylethyl Grignard with vinylbromide and in the hydrosilylation of acetophenone with diphenylsilane.

PHOSPHORORGANISCHE VERBINDUNGEN 105. Synthese chiraler und achiraler ditertiaerer 1-Phosphino-2-Aminoethan-Derivate (=P-CH2-CHR-N=) und einige Anwendungen

Primary amines with an optical active ligand add to vinyl- and propenylphosphonium salts according the reaction schemes (5) and (6), forming compounds of the type E and F.F contains a new asymmetric center in the bridge giving rise to the formation of a mixture of diastereomers, which can be resolved.Phosphonium salts of the type E and F with a benzyl group on the phosphonium center are cleaved reductively by alkali amalgams (Li/Hg; Na/Hg; K/Hg) forming tertiary phosphines with an aminogroup in the β-position.The reductive cleavage with alkali amalgams is superior to the cathodic cleavage.Application: The synthesis of Ni(0)- and Pd(0)-complexes of type J fails.Bis-phosphine complexes of type 21 are formed.The rate of the homogeneous hydrogenation of 1-hexene with Rh(I)-complexes (containing G as a ligand) has an optimum with respect to a Rh/Co-catalyst proportion of 1:2 to 1:1.6.The optical induction of the homogeneous hydrogenation of Z-N-Acylamino-cinnamic acid is lower than 5percent.