7650-91-1

Basic information

• Product Name: BENZYLDIPHENYLPHOSPHINE
• Synonyms: Benzyldiphenylphosphine,98%;BENZYLDIPHENYLPHOSPHINE;Benzyldiphenylphosphine,99%;Diphenyl(phenylmethyl)phosphine;Diphenylbenzylphosphine;Benzyldiphenylphosphine,97%
• CAS NO: 7650-91-1
• Molecular Formula: C₁₉H₁₇P
• Molecular Weight: 276.31
• EINECS: 1312995-182-4
• Product Categories: organophosphorus ligand;Achiral Phosphine;Aryl Phosphine;Basic Phosphine LigandsCatalysis and Inorganic Chemistry;Catalysis and Inorganic Chemistry;Cross-Coupling;Phosphine Ligands;Phosphorus Compounds
• Mol File: 7650-91-1.mol
• Article Data: 30

Chemical Properties

• Melting Point: 77-83 °C(lit.)
• Boiling Point: 399.6 °C at 760 mmHg
• Flash Point: 206.2 °C
• Appearance: White to off-white/Powder
• Vapor Pressure: 3.12E-06mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility: Slightly soluble in water.
• Sensitive: Air Sensitive
• CAS DataBase Reference: BENZYLDIPHENYLPHOSPHINE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYLDIPHENYLPHOSPHINE(7650-91-1)
• EPA Substance Registry System: BENZYLDIPHENYLPHOSPHINE(7650-91-1)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 37/39-26
• WGK Germany: 3
• Hazardous Substances Data: 7650-91-1(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white powder

Uses

Different sources of media describe the Uses of 7650-91-1 differently. You can refer to the following data:
1. suzuki reaction
2. Employed as a catalyst for Suzuki cross-coupling and antiarthritic agent (inhibitor of cathepsin B). It is also used as catalyst in pharmaceutical research.

InChI:InChI=1/C19H17P/c1-4-10-17(11-5-1)16-20(18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15H,16H2

Upstream product

• 4525-46-6 benzyltrimethylammonium iodide 
• 4376-01-6 sodium diphenylphosphide 
• 100-44-7 benzyl chloride 
• 1079-66-9 chloro-diphenylphosphine 
• 829-85-6 diphenylphosphane 
• 100-39-0 benzyl bromide 
• 603-35-0 triphenylphosphine 
• 57170-64-6 1-bromo-2-(diphenylphosphinomethyl)benzene 
• 17154-34-6 (trimethylsilyl)diphenylphosphine 
• 19493-09-5 Methylenetriphenylphosphorane 
• 1100-88-5 benzyltriphenylphosphonium chloride 
• 66310-10-9 N-benzyl-2,4,6-triphenylpyridinium tetrafluoroborate 
• 148185-10-8 diphenylbenzylphosphine borane 
• 98-88-4 benzoyl chloride 

Downstream Products

• 319488-95-4 P(C₆H₅)3NCO₂CH₃CH₂ 
• 56179-23-8 NiCl₂(diphenylbenzylphosphine)2 
• 15683-57-5 Pt3(μ2-CO)3(benzyldiphenylphosphine)3 
• 77382-18-4 dibenzyl diphenyl phosphonium bromide 
• 60607-99-0 trans-dichlorodicarbonylbis(benzyldiphenylphosphine)ruthenium(II) 
• 60661-10-1 cis-dichlorodicarbonylbis(benzyldiphenylphosphine)ruthenium(II) 
• 109215-94-3 Pt₂Cl₄(P(C₆H₁₁)3)2 
• 109215-96-5 PtI₂(P(CH₂C₆H₅)(C₆H₅)2)2 
• 142316-62-9 (C₆H₅CH₂P(C₆H₅)2)2Pt(CH₃C(O)NCH(CH₃)COO) 
• 142340-19-0 (C₆H₅CH₂P(C₆H₅)2)2Pt(CH₃C(O)NCH(CH₂CH₂SCH₃)COO) 
• 61586-06-9 cis-(BzlPh₂P)2PtCl₂ 
• 48239-25-4 PtCl₂(P(CH₂C₆H₅)(C₆H₅)2)2 
• 95357-64-5 (benzyldiphenylphosphane)bis(ethene)nickel 
• 142316-54-9 ((C₆H₅CH₂P(C₆H₅)2)2)Pt(CH₃C(O)NCH₂COO) 

Relevant articles and documents

Phosphastannirane: A phosphorus/tin(II) lewis pair that undergoes alkyne and alkene addition

Bermuda triangle: The first molecule containing a cyclic three-membered Sn-C-P ring has been synthesized and characterized. This SnII-P Lewis pair reacts at room temperature with alkynes and pentene to give the five-membered cyclic addition products. In the case of pentene, this reaction is reversible at room temperature. Trip=2,4,6-iPr3C6H 2. Copyright

A Lewis Base Nucleofugality Parameter, NFB, and Its Application in an Analysis of MIDA-Boronate Hydrolysis Kinetics

The kinetics of quinuclidine displacement of BH3 from a wide range of Lewis base borane adducts have been measured. Parameterization of these rates has enabled the development of a nucleofugality scale (NFB), shown to quantify and predict the leaving group ability of a range of other Lewis bases. Additivity observed across a number of series R′3-nRnX (X = P, N; R′ = aryl, alkyl) has allowed the formulation of related substituent parameters (nfPB, nfAB), providing a means of calculating NFB values for a range of Lewis bases that extends far beyond those experimentally derived. The utility of the nucleofugality parameter is explored by the correlation of the substituent parameter nfPB with the hydrolyses rates of a series of alkyl and aryl MIDA boronates under neutral conditions. This has allowed the identification of MIDA boronates with heteroatoms proximal to the reacting center, showing unusual kinetic lability or stability to hydrolysis.

Palladium-catalyzed C(sp3)–P(III) bond formation reaction with acylphosphines as phosphorus source

Palladium-catalyzed C(sp3)–P(III) bond formation reaction for alkyl substituted phosphines preparation was developed. In this reaction, various alkyl bromides and limited alkyl chlorides reacted with acylphosphine under relative mild and easily accessible condition, and differential phosphines were afforded in good yields. This reaction made up the application of palladium catalysis in C(sp3)–P(III) bond formation, and indicated a practical application of acylphosphine as a phosphination reagent.