87154-97-0Relevant academic research and scientific papers
Electrochemical radical reactions of alkyl iodides: a highly efficient, clean, green alternative to tin reagents
Li, Diyuan,Ma, Tsz-Kan,Scott, Reuben J.,Wilden, Jonathan D.
, p. 5333 - 5338 (2020/06/04)
An electrochemical ‘redox-relay’ system has been developed which allows the generation of C-centered radicals. Intermolecular ‘tin-like’ radical reactions can subsequently be conducted under the most benign of conditions. The yields and efficiency of the processes are competitive and even superior in most cases to comparable conditions with tributyltin hydride. The use of air and electricity as the promotor (instead of a tin or other reagent) combined with the aqueous reaction media make this a clean and ‘green’ alternative to these classic C-C bond forming processes.
Mechanistic Aspects of the Phosphine-Catalyzed Isomerization of Allenic Sulfones to 2-Arylsulfonyl 1,3-Dienes
Hampton, Carissa S.,Harmata, Michael
, p. 12151 - 12158 (2016/01/09)
When an allenic sulfone is treated with a phosphine nucleophile and a proton shuttle, an isomerization to a 2-arylsulfonyl 1,3-diene occurs. Mechanistic aspects of the process were investigated leading to the formulation of a mechanism for the reaction. S
Enantioselective nickel-catalyzed reductive coupling of alkynes and imines
Zhou, Chang-Yue,Zhu, Shou-Fei,Wang, Li-Xin,Zhou, Qi-Lin
supporting information; experimental part, p. 10955 - 10957 (2010/09/17)
The nickel-catalyzed reductive coupling of alkynes and imines with Et 2Zn as a reductant by using electron-rich phosphine ligands has been developed, affording various allylic amines with high yields and excellent chemoselectivities. Chiral induction was also achieved in this reductive coupling reaction when a nickel catalyst containing a chiral spiro phosphine ligand was used.
