871571-01-6Relevant academic research and scientific papers
Rh(III)-catalyzed tandem oxidative olefination-michael reactions between aryl carboxamides and alkenes
Wang, Fen,Song, Guoyong,Li, Xingwei
experimental part, p. 5430 - 5433 (2011/03/19)
Rh(III)-catalyzed oxidative coupling reactions between benzamides or heteroaryl carboxamides and olefins have been developed. The vinylation product can further undergo a Michael reaction leading to γ-lactam in the case of electron-withdrawing olefins.
Palladium mediated synthesis of isoindolinones and isoquinolinones
Wahab Khan,Masud Reza
, p. 11204 - 11210 (2007/10/03)
The palladium-catalyzed reactions of 2-iodo-N-substituted benzamides 5-10 with acrylic esters 11-14 led to N-substituted-3-alkylisoindolinone esters 15-22 in good yields. The esters of isoindolinones 15-22 underwent hydrolysis reactions yielding the N-aryl-1,2,3,4-tetrahydro-1-oxoisoquinoline-3-carboxylic acid 26-31 in good yields.
