871571-28-7

Basic information

• Product Name: 3-Methyl-4-(trifluoroMethyl)benzonitrile
• Synonyms: 3-Methyl-4-(trifluoroMethyl)benzonitrile
• CAS NO: 871571-28-7
• Molecular Weight: 185.149
• Mol File: 871571-28-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-Methyl-4-(trifluoroMethyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-4-(trifluoroMethyl)benzonitrile(871571-28-7)
• EPA Substance Registry System: 3-Methyl-4-(trifluoroMethyl)benzonitrile(871571-28-7)

Safety Data

• Hazardous Substances Data: 871571-28-7(Hazardous Substances Data)

Upstream product

• 1379828-13-3 C₁₄H₂₀N₄ 
• 120120-26-5 (trifluoromethyl)triethylsilane 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 871571-27-6 2-amino-5-methyl-4-trifluoromethyl-benzonitrile 

Downstream Products

• 871571-29-8 4-trifluoromethyl-3-methylbenzoic acid 
• 951232-01-2 3-methyl-4-(trifluoromethyl)benzaldehyde 

Relevant articles and documents

Trifluoromethylation of 1-aryl-3,3-diisopropyltriazenes

A new method for the trifluoromethylation of functionalized aromatic diisopropyltriazenes is described. In a facile two-step, one-pot synthesis, various functionalized trifluoromethyl-substituted arenes are accessible in mostly good yields by using methyl iodide as iodination agent and the trifluoromethylation system (trifluoromethyl)trimethylsilane/potassium fluoride/copper iodide. This concept could be expanded to perfluoroethylation as well as ethoxycarbonyldifluoromethylation reactions. Copyright

Pyrrazolo-pyrimidine derivatives

The present invention relates to pyrrazolo-pyrimidine derivatives of formula (I): wherein R1 to R4 and A are as defined in the specification, a process for the manufacture thereof, their use for treating or preventing metabotropic glutamate receptors mediated disorders, their use for the preparation of medicaments for treating such disorders and pharmaceutical compositions containing said derivatives.

PYRRAZOLO-PYRIMIDINE DERIVATIVES

The invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5 and p are as defined in the description and claims as well as to pharmaceutically acceptable salts thereof per se and as ph