871590-10-2

Upstream product

• 871590-06-6 (5R,6R)-5-(tert-Butyl-dimethyl-silanyloxy)-6-trityloxymethyl-5,6-dihydro-pyran-2-one 
• 15681-48-8 lithium dimethylcuprate 
• 871590-07-7 (2R,3R)-6-(3,4-Dimethoxy-benzyloxy)-2-trityloxymethyl-3,6-dihydro-2H-pyran-3-ol 
• 871590-08-8 tert-butyl-[6-(3,4-dimethoxy-benzyloxy)-2-trityloxymethyl-3,6-dihydro-2H-pyran-3-yloxy]-dimethyl-silane 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 474459-57-9 4-O-mesyl-6-O-trityl-D-glucal 

Downstream Products

• 871590-27-1 3-[(2R,3S,4S,5R,6S)-6-((1S,2R)-1-Benzyloxy-2-methyl-but-3-enyl)-3,4-dimethyl-5-(naphthalen-2-ylmethoxy)-tetrahydro-pyran-2-yl]-propan-1-ol 
• 871590-29-3 (2R,3R,4S,5S,6R)-2-((1S,2R)-1-Benzyloxy-2-methyl-but-3-enyl)-6-[3-(tert-butyl-diphenyl-silanyloxy)-propyl]-4,5-dimethyl-tetrahydro-pyran-3-ol 
• 871590-30-6 (2S,3R,4S,5S,6R)-2-((1S,2R)-1-Benzyloxy-2-methyl-but-3-enyl)-3-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-propyl]-4,5-dimethyl-tetrahydro-pyran 
• 871590-28-2 {3-[(2R,3S,4S,5R,6S)-6-((1S,2R)-1-Benzyloxy-2-methyl-but-3-enyl)-3,4-dimethyl-5-(naphthalen-2-ylmethoxy)-tetrahydro-pyran-2-yl]-propoxy}-tert-butyl-diphenyl-silane 
• 871590-11-3 (3S,4S,5R,6R)-5-(tert-Butyl-dimethyl-silanyloxy)-3,4-dimethyl-6-trityloxymethyl-tetrahydro-pyran-2-one 

Relevant academic research and scientific papers

Synthesis of the C42-C52 part of ciguatoxin CTX3C

The C42-C52 part of ciguatoxin CTX3C (1) was synthesized from tri-O-acetyl d-glucal. The synthetic segment had a tetrahydropyran ring corresponding to the 'C49-reduced' L-ring of 1, designed to avoid side reactions due to acid-labile C49 acetal carbon dur