87165-28-4

Basic information

• Product Name: N-(2-chloro-6-methylphenyl)-2-cyanoacetamide
• Synonyms: acetamide, N-(2-chloro-6-methylphenyl)-2-cyano-; N1-(2-chloro-6-methylphenyl)-2-cyanoacetamide
• CAS NO: 87165-28-4
• Molecular Formula: C₁₀H₉ClN₂O
• Molecular Weight: 208.6443
• Mol File: 87165-28-4.mol

Chemical Properties

• Boiling Point: 400.8°C at 760 mmHg
• Flash Point: 196.2°C
• Density: 1.298g/cm³
• Vapor Pressure: 1.23E-06mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: N-(2-chloro-6-methylphenyl)-2-cyanoacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chloro-6-methylphenyl)-2-cyanoacetamide(87165-28-4)
• EPA Substance Registry System: N-(2-chloro-6-methylphenyl)-2-cyanoacetamide(87165-28-4)

Safety Data

• Hazardous Substances Data: 87165-28-4(Hazardous Substances Data)

Upstream product

• 372-09-8 cyanoacetic acid 
• 87-63-8 2-chloro-6-methylaniline 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 913819-53-1 1-(2-chloro-6-methyl-phenyl)-4-ethyl-5-hydroxy-5-methyl-2-oxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 
• 913819-55-3 4-butyl-1-(2-chloro-6-methyl-phenyl)-5-hydroxy-5-methyl-2-oxo-2,5-dihydro-1H-pyrrole-3-carbonitrile 

Relevant articles and documents

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LIGANDS FOR THE MODULATION OF ECDYSONE RECEPTORS AND CONTROL OF INSECT GROWTH

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Synthesis of N-substituted γ-methylene γ-lactams

N-Substituted cyanoacetamides 1 were condensed with 1,2-diketones 2 under base catalysis to form ?-hydroxy ?-lactams 3. Treatment of 3 with acids gave novel fungicidal ?-methylene ?-lactams 4. The exocyclic double bond of 4b reacted reversibly with 4-toluene sulfinate. CSIRO 2005.