871681-62-8

Basic information

• Product Name: Carbamic acid, (2,5-difluoro-4-hydroxyphenyl)-, phenylmethyl ester
• CAS NO: 871681-62-8
• Molecular Formula: C14H11F2NO3
• Molecular Weight: 279.243
• Mol File: 871681-62-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (2,5-difluoro-4-hydroxyphenyl)-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (2,5-difluoro-4-hydroxyphenyl)-, phenylmethyl ester(871681-62-8)
• EPA Substance Registry System: Carbamic acid, (2,5-difluoro-4-hydroxyphenyl)-, phenylmethyl ester(871681-62-8)

Safety Data

• Hazardous Substances Data: 871681-62-8(Hazardous Substances Data)

Upstream product

• 2105-61-5 1,2,4-trifluoro-5-nitrobenzene 
• 868736-12-3 1-(benzyloxy)-2,5-difluoro-4-nitrobenzene 
• 1275153-32-6 C₁₃H₁₁F₂NO 
• 501-53-1 benzyl chloroformate 
• 120103-19-7 4-amino-2,5-difluorophenol 
• 3459-92-5 DBC 

Downstream Products

• 928038-45-3 benzyl [4-(4-chloropyrimidin-6-yloxy)-2,5-difluorophenyl]carbamate 
• 928038-46-4 Benzyl [4-(4-aminopyrimidin-6-yloxy)-2,5-difluorophenyl]carbamate 
• 928038-47-5 Benzyl [4-(4-azidopyrimidin-6-yloxy)-2,5-difluorophenyl]carbamate 
• 928038-48-6 4-amino-6-(4-amino-2,5-difluorophenoxy)pyrimidine 
• 834154-72-2 2,5-difluoro-4-propoxy-phenylamine 

Relevant articles and documents

PYRIDINE OR PYRIMIDINE DERIVATIVE HAVING EXCELLENT CELL GROWTH INHIBITION EFFECT AND EXCELLENT ANTI-TUMOR EFFECT ON CELL STRAIN HAVING AMPLIFICATION OF HGFR GENE

A pyridine or pyrimidine derivative represented by the formula (I) has an excellent HGFR inhibitory activity and exhibits strong cell proliferation inhibitory effect and anti-tumor effect against cancer cell lines with amplified HGFR gene. wherein R1 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; R2 and R3 represent hydrogen; R4, R5, R6, and R7 may be the same or different and each represents hydrogen, halogen, C1-6 alkyl or the like; R8 represents hydrogen or the like; R9 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; n represents an integer of 1 or 2; X represents -CH=, nitrogen.

SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO

The present invention relates to certain substituted aryl and heteroaryl derivative of Formula (I) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and complicati