871700-22-0 Usage
Uses
3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)-2,4(1H,3H)-pyrimidinedione acts as a reagent in the preparation of 5-amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2H-pyrido[2,3-d]pyrimidine derivatives and related compounds for the treatment of cancer and rheumatic diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 871700-22-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,7,0 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 871700-22:
(8*8)+(7*7)+(6*1)+(5*7)+(4*0)+(3*0)+(2*2)+(1*2)=160
160 % 10 = 0
So 871700-22-0 is a valid CAS Registry Number.
871700-22-0Relevant articles and documents
Method for synthesizing key intermediate of trametinib
-
Paragraph 0029, (2019/02/27)
The invention discloses a method for synthesizing a key intermediate of trametinib, malonic acid monomethyl amide monoethyl ester and isosuccinic acid have a ring-closure reaction to obtain a crude product of a pyridine triketone compound; the obtained cr