871709-97-6

Upstream product

• 105942-08-3 4-bromo-6-fluorobenzonitrile 
• 884874-98-0 2-fluoro-5-(5-formylfuran-2-yl)-benzonitrile 
• 214210-21-6 3-cyano-4-fluorophenylboronic acid 
• 585-70-6 5-bromo-furan-2-carboxylic acid 

Downstream Products

• 871708-18-8 5-(3-amino-1H-indazol-5-yl)-furan-2-carboxylic acid 
• 871709-81-8 C₁₂H₉N₃O₃ 

Relevant academic research and scientific papers

INDAZOLE-HETEROARYL DERIVATIVES

The invention relates to novel indazole derivatives as cited in claim 1, which are inhibitors of CHK1, CHK2 and SGK kinases and can be used to treat cancer and other diseases.

HETEROCYCLIC CARBONYL COMPOUNDS

The invention relates to novel heterocyclic compounds of formula (I) wherein R1, D, W, T and T' have the meaning cited in the claim 1. Said compounds are SGK-inhibitors and can be used in the treatment of SGK-related diseases and disorders such as diabetes, obesity, metabolic syndrome (dyslipidemia), systemic and pulmonal hypertension, cardiovascular diseases and renal diseases, and generally for any kind of fibroses and inflammatory processes.

3-AMINOINDAZOLES

Novel 3-aminoindazoles of formula (I) are SGK-inhibitors and can be used for treating SGK-related diseases and illnesses such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, and generally any type of fibroses and inflammatory processes.