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1-Pyrrolidinecarboxylic acid, 2-(chloroacetyl)-, 1,1-dimethylethyl ester, (2R)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

871716-67-5

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871716-67-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 871716-67-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,7,1 and 6 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 871716-67:
(8*8)+(7*7)+(6*1)+(5*7)+(4*1)+(3*6)+(2*6)+(1*7)=195
195 % 10 = 5
So 871716-67-5 is a valid CAS Registry Number.

871716-67-5Relevant academic research and scientific papers

PROTEIN SECRETION INHIBITORS

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Paragraph 00205, (2022/03/09)

Provided herein are secretion inhibitors, such as inhibitors of Sec61 for example of Formula (I), methods for their preparation, related pharmaceutical compositions, and method for using the same.

THIAZOLE DERIVATIVES AS PROTEIN SECRETION INHIBITORS

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Paragraph 00260; 00340, (2020/09/12)

Provided herein are secretion inhibitors, such as inhibitors of Sec61, methods for their preparation, related pharmaceutical compositions, and methods for using the same, wherein the compound has a structure of Formula (I), (II), or (III).

2-(2-Aminothiazol-4-yl)pyrrolidine-based tartrate diamides as potent, selective and orally bioavailable TACE inhibitors

Dai, Chaoyang,Li, Dansu,Popovici-Muller, Janeta,Zhao, Lianyun,Girijavallabhan, Vinay M.,Rosner, Kristin E.,Lavey, Brian J.,Rizvi, Razia,Shankar, Bandarpalle B.,Wong, Michael K.C.,Guo, Zhuyan,Orth, Peter,Strickland, Corey O.,Sun, Jing,Niu, Xiaoda,Chen, Shiying,Kozlowski, Joseph A.,Lundell, Daniel J.,Piwinski, John J.,Shih, Neng-Yang,Siddiqui, M. Arshad

scheme or table, p. 3172 - 3176 (2011/06/24)

TNF-α converting enzyme (TACE) inhibitors are promising agents to treat inflammatory disorders and cancer. We have investigated novel tartrate diamide TACE inhibitors where the tartrate core binds to zinc in a unique tridentate fashion. Incorporating (R)-

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