871794-92-2Relevant academic research and scientific papers
Use of Inhibitors of the Activity or Function of PI3K
-
Paragraph 0857-0858, (2016/01/09)
The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.
QUINAZOLINE DERIVATIVES AS PI3K MODULATORS
-
Page/Page column 48-49, (2013/05/09)
The invention relates to substituted quinazoline derivative of the formula (I), wherein A, X1, X2, X3, X4 and R5 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.
Use of inhibitors of the activity or function of PI3K
-
Page/Page column 95; 96, (2013/07/05)
The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.
HETEROCYCLIC COMPOUND
-
Page/Page column 69, (2011/04/18)
The present invention relates to a compound represented by wherein each symbol is as defined in the specification, a salt thereof and the like.
HETEROCYCLIC COMPOUND
-
Page/Page column 50, (2011/10/19)
The present invention relates to a compound represented by wherein each symbol is as defined in the specification, a salt thereof and the like.
4-PHENYL-PYRIMIDINE-2-CARBONITRILE DERIVATIVES
-
Page/Page column 51, (2008/06/13)
The invention relates to 4-phenyl-pyrimidine-2-carbonitrile derivatives having the general formula (I) or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising said derivatives as well as to the use thereof in the preparation of a medicament suitable for the treatment of osteoporosis, atherosclerosis, inflammation and immune disorders, such as rheumatoid arthritis, and chronic pain, such as neuropathic pain.
