87181-27-9

Upstream product

• 93135-45-6 2,3-dichloro-4-ethoxybenzenesulfonyl chloride 
• 87181-26-8 2,3-dichloro-4-ethoxybenzenethiol 
• 350-46-9 4-Fluoronitrobenzene 
• 87181-25-7 2,3-dichloro-4-<(4-nitrophenyl)sulfenyl>phenetole 

Downstream Products

• 87181-33-7 ethyl <2,3-dichloro-4-<<3-(aminomethyl)-4-hydroxyphenyl>sulfenyl>phenoxy>acetate hydrochloride 
• 87181-37-1 methyl <2,3-dichloro-4-<<3-(aminomethyl)-4-hydroxyphenyl>sulfinyl>phenoxy>acetate hydrochloride 
• 93134-88-4 {4-[3-(tert-Butoxycarbonylamino-methyl)-4-(2-methoxy-ethoxymethoxy)-benzenesulfinyl]-2,3-dichloro-phenoxy}-acetic acid ethyl ester 
• 93134-87-3 {4-[3-(tert-Butoxycarbonylamino-methyl)-4-(2-methoxy-ethoxymethoxy)-phenylsulfanyl]-2,3-dichloro-phenoxy}-acetic acid ethyl ester 
• 93135-28-5 ethyl <2,3-dichloro-<4-hydroxy-3-<(tert-butoxycarbonyl)aminomethyl>phenylthio>phenoxy>acetate 
• 87181-31-5 ethyl <2,3-dichloro-4-<4-hydroxy-3-<(2-chloroacetyl)aminomethyl>phenylthio>phenoxy>acetate 
• 93135-27-4 <2,3-dichloro-4-<4-hydroxy-3-<(2-chloroacetyl)aminomethyl>phenylthio>phenoxy>acetic acid 
• 87181-29-1 ethyl <2,3-dichloro-4-<(4-hydroxyphenyl)sulfenyl>phenoxy>acetate 
• 93135-25-2 ethyl <2,3-dichloro-4-(4-aminophenylthio)phenoxy>acetate 
• 87181-30-4 <2,3-dichloro-4-(4-hydroxyphenylthio)phenoxy>acetic acid 
• 87181-28-0 ethyl <2,3-dichloro-4-<(4-nitrophenyl)sulfenyl>phenoxy>acetate 

Relevant academic research and scientific papers

[(Aminomethyl)aryloxy]acetic acid esters. A new class of high-ceiling diuretics. 3. Variation in the bridge between the aromatic rings to complete mapping of the receptor

Continued structural evaluation of the [(aminomethyl)aryloxy]acetic ester diuretics has produced a series of compounds in which the functional group that bridges the two aromatic rings has been varied. Diuretic screening of these analogues in rats indicat

Diphenyl ether, diphenyl thioether and diphenyl methane phenol mannich bases

Described are compounds of the formula STR1 wherein R is hydrogen, loweralkyl, aminomethyl or halo; R1 is carboxy, carboxyloweralkyl, aminocarbonyl, hydroxymethyl, anilinomethyl, or aminomethyl; A is oxygen, CH2, Sulfur or a single bond; X is oxygen, CH2, sulfur or sulfoxide; and Y is hydrogen, loweralkyl or halo and may be the same or different, and pharmaceutically acceptable salts thereof. The compounds are effective as diuretic agents.