871813-92-2Relevant academic research and scientific papers
DNA binding potential and cytotoxicity of newly designed pyrrolobenzodiazepine dimers linked through a piperazine side-armed-alkane spacer
Kamal, Ahmed,Murali Mohan Reddy,Rajasekhar Reddy,Laxman
, p. 385 - 394 (2007/10/03)
New pyrrolobenzodiazepine (PBD) dimers have been developed that are composed of two DC-81 subunits tethered to their C8 positions through piperazine moiety side-armed with alkaneoxy linkers (composed of 2-5 carbons). DNA thermal denaturation studies show
