87184-62-1Relevant academic research and scientific papers
A study of the intramolecular cyclization reactions of some derivatives of 3-arylsulfonyl cycloalkanols
Gonzales, Stephen S.,Jacobs, Hollie K.,Juarros, LuAnne E.,Gopalan, Aravamudan S.
, p. 6827 - 6830 (1996)
Carbonate and acyl derivatives of 3-arylsulfonylcyclohexanols and heptanols, upon deprotonation with LHMDS in THF at -78°C, undergo an intramolecular cyclization reaction to give bicyclic lactones or the corresponding acyl transfer products in synthetically useful yields. In contrast, the corresponding cyclopentyl derivatives show different reactivity.
Ethyl glyoxylate N -tosylhydrazone as sulfonyl-transfer reagent in base-catalyzed sulfa-Michael reactions
Fernandez, Maitane,Uria, Uxue,Orbe, Lucia,Vicario, Jose L.,Reyes, Efraim,Carrillo, Luisa
, p. 441 - 445 (2014/01/17)
Ethyl glyoxylate N-tosylhydrazone has been identified as an excellent sulfonyl anion surrogate in the DBU-catalyzed conjugate addition reaction with enones and enals for the synthesis of functionalized sulfones. The reaction proceeds under base-catalyzed conditions and provides a direct access to γ-keto- and γ-hydroxy sulfones in a simple and reliable way through a sulfa-Michael reaction that proceeds with high yield and chemoselectivity.
Preparation and Stereochemistry of Methylation of Some Cycloalkyl Sulfones
Rothberg, Irvin,Sundoro, Boby,Balanikas, George,Kirsch, Sheldon
, p. 4345 - 4348 (2007/10/02)
3-((4-methylphenyl)sulfonyl)cyclohexanols (2, 3), 3-((4-methylphenyl)sulfonyl)cyclopentanols (7, 8), and 2-((4-methylphenyl)sulfonyl)cyclopentanols (12, 15) and their tetrahydropyranyl ether derivatives were prepared.Attempted methylation of the tetrahydr
