1346155-98-3

Upstream product

• 87184-80-3 5-tert-butyldimethylsilyloxypentanal 
• 536-74-3 phenylacetylene 
• 83067-20-3 5-(tert-butyldimethyl-silyloxy)pentan-1-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 111-29-5 1 ,5-pentanediol 

Downstream Products

• 1346155-64-3 1-(4-tert-butyldimethylsiloxybutyl)-1H-inden-3-yl benzoate 
• 1346155-36-9 7-tert-butyldimethylsiloxy-1-phenylhept-1-yn-3-yl benzoate 

Relevant academic research and scientific papers

Regioselective cyclizations utilizing a gold-catalyzed [3,3] propargyl ester rearrangement

Switch-Au-roo: A new strategy for the regioselective synthesis of unsaturated carbocycles by chemoselective activation of a Rauhut-Currier zwitterion surrogate, formed from the Au-catalyzed [3,3] sigmatropic rearrangement of propargylic esters, has been achieved. By reversing the regiochemistry of the propargyl ester the synthesis of either the endo- or exocyclic enones is feasible.

Vicinal bisheterocyclizations of alkynes via nucleophilic interception of a catalytic platinum carbene

A novel platinum-catalyzed double heterocyclization of propargylic ethers is described. The transformation exploits the intermediacy of a key α,β-unsaturated carbene. The reactivity of this carbene is such that systems can be developed which avoid a complicating 1,2-hydrogen migration, allowing remarkable versatility in the selective syntheses of oxygen- and nitrogen-containing vicinal bis-heterocyclic compounds.

PtI2-Catalyzed tandem 3,3-rearrangement/Nazarov reaction of arylpropargylic esters: Synthesis of indanone derivatives

An efficient PtI2-catalyzed tandem reaction of arylpropargylic esters, involving 3,3-rearrangement and Nazarov reaction, has been developed to produce 3-substituted and 3,3-disubstituted indanone derivatives. This approach provided a pathway to the synthesis of indanone skeletons in natural products.