871928-49-3

Upstream product

• 87815-77-8 4-cyclohexylamino-3-nitrobenzoic acid ethyl ester 
• 347174-05-4 3-Amino-4-cyclohexylamino benzoic acid ethyl ester 
• 108-91-8 cyclohexylamine 
• 16588-16-2 ethyl 4-chloro-3-nitrobenzoate 

Downstream Products

• 871928-47-1 1-cyclohexyl-2-(morpholin-4-yl)-1H-benzimidazole-5-carboxylic acid 
• 871930-68-6 1-cyclohexyl-2-morpholin-4-yl-1H-benzimidazole-5-carboxylic acid (2-oxo-ethyl)-amide 
• 871930-70-0 5-(5-bromo-oxazol-2-yl)-1-cyclohexyl-2-morpholin-4-yl-1H-benzimidazole 
• 871928-50-6 1-cyclohexyl-2-(morpholin-4-yl)-1H-benzimidazole-5-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

five Yuan fragrance heterocyclic structure containing the anti-hepatitis c compound and its preparation and use

The invention discloses an anti-HCV (hepatitis C) compound containing a five-membered heteroaromatic ring structure, as well as a preparation method and applications thereof. The compound has a structure shown as the formula I, the compound has excellent anti-HCV virus activity, can be used for preparing anti-HCV drugs, the prepared drugs can be applied by adopting oral administration, intravenous injection or intramuscular injection.

FUSED HETEROCYCLIC COMPOUND HAVING ANTI-HCV EFFECT

Disclosed is a compound represented by the formula (I) below, a pharmaceutically acceptable salt thereof, or a solvate of them. (I) (In the formula, A represents N or CH; Het represents any one of the following groups: (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k) wherein R0 and R respectively represent a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted aryl or the like; R1 and R2 respectively represent a hydrogen, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted cycloalkyl, an optionally substituted aryl, an optionally substituted heteroaryl or the like; p is an integer of 0-3; and R3 represents an optionally substituted alkyl or the like.)